18759-96-1

Basic information

• Product Name: 3-Aminobenzylmethylamine
• Synonyms: 3-AMINOBENZYLMETHYLAMINE;3-AMINO-N-METHYLBENZYLAMINE;3-amino-n-monomethylbenzylamine;3-[(methylamino)methyl]aniline;3-Amino-N-benzylamine;3-methylaminomethylphenylamine;3-Amino-N-methylbenzylamine ,98％;BenzeneMethanaMine, 3-aMino-N-Methyl-
• CAS NO: 18759-96-1
• Molecular Formula: C₈H₁₂N₂
• Molecular Weight: 136.19
• EINECS: 414-570-7
• Product Categories: Amine;Amines
• Mol File: 18759-96-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 34 °C
• Boiling Point: 248.868 °C at 760 mmHg
• Flash Point: 34 °C
• Appearance: /
• Density: 1.021 g/cm³
• Vapor Pressure: 0.024mmHg at 25°C
• Refractive Index: 1.568
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 9.72±0.10(Predicted)
• CAS DataBase Reference: 3-Aminobenzylmethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Aminobenzylmethylamine(18759-96-1)
• EPA Substance Registry System: 3-Aminobenzylmethylamine(18759-96-1)

Safety Data

• Hazard Codes: C,N
• Statements: 21/22-34-43-50/53
• Safety Statements: 26-36/37/39-45-60-61
• RIDADR: 3259
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 18759-96-1(Hazardous Substances Data)

Usage

General Description

3-Aminobenzylmethylamine is a chemical compound with the molecular formula C9H13N. It is a derivative of benzylamine and is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. 3-Aminobenzylmethylamine is a clear, colorless to pale yellow liquid with a faint amine odor. 3-Aminobenzylmethylamine is primarily used as a building block in organic synthesis and is known for its role as a versatile intermediate in the production of a wide range of chemicals. It is important to handle this compound with care, and proper safety precautions should be taken when working with it in laboratory or industrial settings.

InChI:InChI=1/C8H12N2/c1-10-6-7-3-2-4-8(9)5-7/h2-5,10H,6,9H2,1H3

Upstream product

• 25900-61-2 3-amino-N-methylbenzamide 
• 67344-77-8 1-(3-bromophenyl)-N-methylmethanamine 
• 39191-07-6 3-chloro-N-methylbenzylamine 

Relevant articles and documents

Mild and highly selective palladium-catalyzed monoarylation of ammonia enabled by the use of bulky biarylphosphine ligands and palladacycle precatalysts

A method for the Pd-catalyzed arylation of ammonia with a wide range of aryl and heteroaryl halides, including challenging five-membered heterocyclic substrates, is described. Excellent selectivity for monoarylation of ammonia to primary arylamines was achieved under mild conditions or at rt by the use of bulky biarylphosphine ligands (L6, L7, and L4) as well as their corresponding aminobiphenyl palladacycle precatalysts (3a, 3b, and 3c). As this process requires neither the use of a glovebox nor high pressures of ammonia, it should be widely applicable.

A P,N-Ligand for palladium-catalyzed ammonia arylation: Coupling of deactivated aryl chlorides, chemoselective arylations, and room temperature reactions

(Figure Presented) Amazing ammonia: A new air-stable P,N-ligand (Mor-DalPhos) is reported that enables the palladium-catalyzed crosscoupling of ammonia to a variety of aryl chloride and aryl tosylate substrates with high chemoselectivity and, for the first time, at room temperature (see scheme; Ad = adamantyl, Ts=para-toluenesulfonyl).