187672-34-0

Upstream product

• 2124-31-4 4'-dimethylaminoacetophenone 

Downstream Products

• 1159490-62-6 4-dimethylaminoacetophenone O-vinyloxime 
• 1159490-63-7 C₁₄H₁₆N₂ 
• 324740-69-4 2-[4-(N,N-dimethylamino)phenyl]-1H-pyrrole 
• 7463-28-7 N'-acetyl-N,N-dimethyl-1,4-phenylenediamine 

Relevant academic research and scientific papers

An efficient catalytic method for the Beckmann rearrangement of ketoximes to amides and aldoximes to nitriles mediated by propylphosphonic anhydride (T3P)

An efficient method for the Beckmann rearrangement of ketoximes to amides mediated by a catalytic amount (15 mol %) of propylphosphonic anhydride (T3P) is described. Aldoximes underwent second order Beckmann rearrangement to provide the corresponding nitriles in excellent yields on reacting with T3P (15 mol %) at room temperature. The main advantages of this environmentally friendly protocol include procedural simplicity, and particularly ease of isolation of the products.

4-Dimethylaminoacetophenone O-vinyloxime: Synthesis and steric structure

4-Dimethylaminoacetophenone oxime was synthesized from 4- dimethylaminoacetophenone and hydroxylamine hydrochloride. Its reaction with acetylene in the system KOH-DMSO gave previously unknown 4- dimethylaminoacetophenone O-vinyloxime as the major product.

1H and 13C studies of para-substituted benzaldoximes for evaluation of the electron donor properties of substituted amino groups

1H and 13C NMR spectra of seventeen (E)-benzaldoximes and three acetophenone oximes, both carrying substituted p-amino groups, have been recorded and discussed from the point of view of substituent effect.The resonance effect of these substituents is not transmitted strongly to CH=NOH group.However, it is found that the chemical shift of Cpara depends linearly on ?R0 values.This dependence has been used to calculate the resonance substituent constants for the less common amino groups and the 1-pyrrolidine group is found to be the most powerful electron donor among the substituents studied.