18769-24-9 Usage
Chemical class
Corticosteroids
Derivative of
Hydrocortisone
Function
Regulates physiological processes
Medical use
Anti-inflammatory and immunosuppressant properties
Common treatments
Asthma, arthritis, and skin disorders
21-acetate form
Improved stability and prolonged duration of action
Pharmaceutical ingredient
Widely used in the management of inflammatory diseases
These properties and contents are based on the information provided in the material, which describes 16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-acetate as a synthetic corticosteroid derived from hydrocortisone. It is used in medicine for its anti-inflammatory and immunosuppressant properties, particularly in the treatment of asthma, arthritis, and skin disorders. The 21-acetate form of the compound provides improved stability and a longer duration of action, making it an effective pharmaceutical ingredient for managing inflammatory diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 18769-24-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,7,6 and 9 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 18769-24:
(7*1)+(6*8)+(5*7)+(4*6)+(3*9)+(2*2)+(1*4)=149
149 % 10 = 9
So 18769-24-9 is a valid CAS Registry Number.
18769-24-9Relevant articles and documents
Synthesis method of beclomethasone dipropionate intermediate 11 - β hydroxypregnane
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Paragraph 0011; 0033; 0047-0065, (2020/10/30)
The invention belongs to the field of a medicine preparation, and particularly relates to a synthesis method of an alclometasone dipropionate intermediate of 11-beta hydroxypregna. The 11-beta hydroxypregna is obtained by using a compound shown as a formula II as raw materials and performing free radical reaction under the effects of zinc powder, hexahydrate chromium trichloride and thioglycolic acid. The method provided by the invention has the advantages that the operation is simple; the yield is high; the method is suitable for industrial production.
