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Ethyl 4-hydroxy-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate is a pyrrolopyrimidine derivative with the molecular formula C10H10N4O3. It is a chemical compound that exhibits a range of biological activities, such as anti-inflammatory and antitumor properties. Its structural features, including the ethyl ester group attached to the carboxylate functional group, make it a valuable target for drug discovery and development.

187724-99-8

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187724-99-8 Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 4-hydroxy-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate is used as a building block for the synthesis of novel drug candidates due to its potential pharmaceutical applications. Its diverse range of biological activities, including anti-inflammatory and antitumor properties, make it a promising candidate for the development of new therapeutic agents.
Used in Medicinal Chemistry Research:
Ethyl 4-hydroxy-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate is used as a research compound in medicinal chemistry to explore its potential as a precursor for the synthesis of new drugs. Its structural features and lipophilic nature, facilitated by the ethyl ester group, allow for its incorporation into various drug formulations, enhancing its potential in drug discovery and development.

Check Digit Verification of cas no

The CAS Registry Mumber 187724-99-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,7,2 and 4 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 187724-99:
(8*1)+(7*8)+(6*7)+(5*7)+(4*2)+(3*4)+(2*9)+(1*9)=188
188 % 10 = 8
So 187724-99-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H9N3O3/c1-2-15-9(14)6-3-5-7(12-6)10-4-11-8(5)13/h3-4H,2H2,1H3,(H2,10,11,12,13)

187724-99-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Ethyl 4-hydroxy-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate

1.2 Other means of identification

Product number -
Other names ethyl 4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidine-6-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:187724-99-8 SDS

187724-99-8Relevant academic research and scientific papers

Substituted pyrrolopyrimidines and processes for their preparation

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, (2008/06/13)

There are described 7H-pyrrolo[2,3-d]pyrimidine derivatives of the formula I in which the substituents are as defined in claim 1. These compounds inhibit the tyrosine kinase activity of the receptor for the epidermal growth factor (EGF) and c-erbB2 kinase and can be used as anti-tumor agents.

Pyrrolopyrimidines and processes for the preparation thereof

-

, (2008/06/13)

PCT No. PCT/EP96/02728 Sec. 371 Date Jan. 26, 1998 Sec. 102(e) Date Jan. 26, 1998 PCT Filed Jun. 24, 1996 PCT Pub. No. WO97/02266 PCT Pub. Date Jan. 23, 1997Described are 7H-pyrrolo[2,3-d]pyrimidine derivatives of formula I wherein the symbols are as defined in claim 1. Those compounds inhibit tyrosine protein kinase and can be used in the treatment of hyperproliferative diseases, for example tumour diseases.

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