187739-96-4Relevant academic research and scientific papers
Practical synthetic route to benzimidazole-2-carboxylate derivatives via I2-induced overall 5-endo-trig cyclization
Yukawa, Hirotaka,Nagatani, Takeshi,Torisawa, Yasuhiro,Okaichi, Yoshihiko,Tada, Nobuhito,Furuta, Takuya,Minamikawa, Jun-ichi,Nishi, Takao
, p. 1267 - 1268 (1997)
A practical synthetic route far benzimidazole-2-carboxylate derivatives has been developed, in which an iodine-induced 5-endo-trig cyclization path is involved as a key step.
Method of inhibiting neoplastic cells with benzimidazole derivatives
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, (2008/06/13)
A method for inhibiting neoplasia, particularly cancerous and precancerous lesions by exposing the affected cells to benzimidazole derivatives.
Benzimidazole derivatives
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, (2008/06/13)
The present invention provides novel benzimidazole derivatives or salts thereof represented by the general formula, STR1 wherein R1 is a hydrogen atom or a halogen atom; R2 is a phenyl-lower alkyl group; R3 is a heterocyclic group selected from the group consisting of an indolyl group, indolinyl group, 1H-indazolyl group, 2(1H)-quinolinonyl group, 3,4-dihydro-2(1H)-quinolinonyl group and 1,4-benzoxazinyl group; A is a lower alkylene group; n is 0 or 1. The benzimidazole derivatives or salts of the present invention are effective agents for treating various arteriosclerotic diseases.
