187744-53-2 Usage
Classification
Thiadiazole derivative
Structure
Heterocyclic organic compound with a five-membered ring containing a sulfur atom, two nitrogen atoms, and an amino group
Substituent
4-methylphenyl group attached to the second carbon atom of the thiadiazole ring
Biological activities
Antibacterial, antifungal, and anticancer properties
Applications
Pharmaceutical research, materials science, agrochemicals
Check Digit Verification of cas no
The CAS Registry Mumber 187744-53-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,7,4 and 4 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 187744-53:
(8*1)+(7*8)+(6*7)+(5*7)+(4*4)+(3*4)+(2*5)+(1*3)=182
182 % 10 = 2
So 187744-53-2 is a valid CAS Registry Number.
187744-53-2Relevant articles and documents
Syntheses of arylsulfonyl-1,3,4-thiadiazoles
Shafiee,Foroumadi
, p. 1611 - 1614 (2007/10/03)
Reaction of sodium arylsulfinate with 2-aryl-5-chloro-1,3,4-thiadiazole gave 2-aryl-5-arylsulfonyl-1,3,4-thiadiazole (3) in good yield. Starting from readily available 2-amino-5-benzylmercapto-1,3,4-thiadiazole compound 7 was obtained in three steps in moderate yield. Reaction of compound 7 with sodium arylsulfinate afforded 2,5-diarylsulfonyl-1,3,4-thiadiazole (11). Oxidation of compound 10 with hydrogen peroxide in acetic acid gave 2-arylsulfonyl-5-benzylsulfonyl-1,3,4-thiadiazole (12), in high yield.
