187795-87-5Relevant academic research and scientific papers
Highly selective C-H functionalization/halogenation of acetanilide
Wan, Xiaobing,Ma, Zhongxun,Li, Bijie,Zhang, Keya,Cao, Shaokui,Zhang, Shiwei,Shi, Zhangjie
, p. 7416 - 7417 (2007/10/04)
Highly regioselective C-H functionalization/halogenation of acetanilides to produce ortho-haloacetanilides was catalyzed by Pd(OAc)2 and Cu(OAc)2 with CuX2 as the halogen source. Copyright
Brominated trimetrexate analogues as inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase
Rosowsky, Andre,Mota, Clara E.,Queener, Sherry F.
, p. 1959 - 1966 (2007/10/03)
Five previously undescribed trimetrexate analogues with bulky 2'-bromo substitution on the phenyl ring were synthesized in order to assess the effect of this structure modification on dihydrofolate reductase inhibition. Condensation of 2-[2-(2-bromo-3,4,5
