187803-41-4Relevant academic research and scientific papers
Synthesis and antimicrobial activity of δ-viniferin analogues and isosteres
Catinella, Giorgia,Dallavalle, Sabrina,Krogfelt, Karen Angeliki,Mattio, Luce Micaela,Musso, Loana,Pedersen, Kasandra Juliet,Pinna, Cecilia,Pinto, Andrea
, (2021/12/24)
The natural stilbenoid dehydro-δ-viniferin, containing a benzofuran core, has been recently identified as a promising antimicrobial agent. To define the structural elements relevant to its activity, we modified the styryl moiety, appended at C5 of the ben
Synthesis, electrochemistry and anticancer activity of novel ferrocenyl phenols prepared via azide-alkyne 1,3-cycloaddition reaction
Plazuk, Damian,Rychlik, B?azej,B?auz, Andrzej,Domaga?a, S?awomir
, p. 102 - 112 (2012/09/07)
A series of monophenols and diphenols containing the ferrocene-C triazolyl and ferrocene-Ntriazolyl bond were prepared in a cycloaddition reaction of ethynylferrocene with aryl and benzyl azides and in a reaction of azidoferrocene with phenylacetylenes, respectively. The anticancer activity of the prepared compounds against hormone-dependent (MCF-7) and hormone-independent (HCC38) breast cancer cell lines was studied. The investigated compounds exhibited moderate anticancer activity against hormone-independent (IC50 ~ 15-48 μM) cancer cell line and low activity against hormone-dependent cancer cell line (IC50 ~ 84-98 μM).
End-cap stabilized oligoynes: Model compounds for the linear sp carbon allotrope carbyne
Gibtner, Thomas,Hampel, Frank,Gisselbrecht, Jean-Paul,Hirsch, Andreas
, p. 408 - 432 (2007/10/03)
Three series of differently 3,5-disubstituted α,ω-diphenylpolyynes Ar-(C≡C)n-Ar (n=2, 4, 6, 8, 10) were synthesized under optimized Cadiot - Chodkiewicz conditions, isolated and completely characterized. These compounds can be considered as mod
