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187803-40-3

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187803-40-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 187803-40-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,8,0 and 3 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 187803-40:
(8*1)+(7*8)+(6*7)+(5*8)+(4*0)+(3*3)+(2*4)+(1*0)=163
163 % 10 = 3
So 187803-40-3 is a valid CAS Registry Number.

187803-40-3Relevant articles and documents

Small Molecule Inhibitors of the Bacterioferritin (BfrB)-Ferredoxin (Bfd) Complex Kill Biofilm-Embedded Pseudomonas aeruginosa Cells

Soldano, Anabel,Yao, Huili,Punchi Hewage, Achala N. D.,Meraz, Kevin,Annor-Gyamfi, Joel K.,Bunce, Richard A.,Battaile, Kevin P.,Lovell, Scott,Rivera, Mario

, p. 123 - 140 (2020/12/21)

Bacteria depend on a well-regulated iron homeostasis to survive adverse environments. A key component of the iron homeostasis machinery is the compartmentalization of Fe3+ in bacterioferritin and its subsequent mobilization as Fe2+ to satisfy metabolic requirements. In Pseudomonas aeruginosa Fe3+ is compartmentalized in bacterioferritin (BfrB), and its mobilization to the cytosol requires binding of a ferredoxin (Bfd) to reduce the stored Fe3+ and release the soluble Fe2+. Blocking the BfrB-Bfd complex in P. aeruginosa by deletion of the bfd gene triggers an irreversible accumulation of Fe3+ in BfrB, concomitant cytosolic iron deficiency and significant impairment of biofilm development. Herein we report that small molecules developed to bind BfrB at the Bfd binding site block the BfrB-Bfd complex, inhibit the mobilization of iron from BfrB in P. aeruginosa cells, elicit a bacteriostatic effect on planktonic cells, and are bactericidal to cells embedded in mature biofilms.

Synthesis and antimicrobial activity of δ-viniferin analogues and isosteres

Catinella, Giorgia,Dallavalle, Sabrina,Krogfelt, Karen Angeliki,Mattio, Luce Micaela,Musso, Loana,Pedersen, Kasandra Juliet,Pinna, Cecilia,Pinto, Andrea

supporting information, (2021/12/24)

The natural stilbenoid dehydro-δ-viniferin, containing a benzofuran core, has been recently identified as a promising antimicrobial agent. To define the structural elements relevant to its activity, we modified the styryl moiety, appended at C5 of the ben

Total Synthesis of Two Glycosylated Stilbenes, Oxyresveratrol 2-O-β- d -Glucopyranoside and 2,3,5,4′-Tetrahydroxystilbene 2-O-β- d -Glucopyranoside

Kumar, Sunil,Lee, Hsueh-Yun,Liou, Jing-Ping

, p. 1294 - 1301 (2017/05/31)

Glycosylated stilbenes are biologically active secondary metabolites of plants and have the potential to alleviate a broad range of human diseases. However, some of these compounds are not naturally abundant, and thus the synthesis of such molecules is de

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