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Usage

Uses

Used in Flavor and Fragrance Industry:
(R)-1-(3-bromophenyl)ethyl acetate is used as a key component in the flavor and fragrance industry, particularly for the production of perfumes and other scented products. Its strong, sweet, and floral odor makes it a valuable addition to the creation of various fragrances, enhancing the sensory experience of consumers.
Used as a Chemical Intermediate:
In the realm of chemical synthesis, (R)-1-(3-bromophenyl)ethyl acetate serves as an essential intermediate. It is utilized in the production of other compounds, contributing to the development of a wide range of products in the chemical industry.
Used in Pheromone Production:
(R)-1-(3-bromophenyl)ethyl acetate also finds application in the field of biology, specifically as a pheromone. It acts as a sex attractant for certain insect species, playing a crucial role in their mating and reproductive processes. This application highlights the compound's ability to influence natural behaviors, making it an important tool in biological research and pest control strategies.

Upstream product

• 108-05-4 vinyl acetate 
• 52780-14-0 1-(3-bromophenyl)ethanol 
• 2142-63-4 1-(3-Bromophenyl)ethanone 
• 108-22-5 Isopropenyl acetate 
• 108-24-7 acetic anhydride 
• 52780-14-0 (R)-1-(3-bromophenyl)ethanol 

Relevant academic research and scientific papers

CO2-expanded liquids as solvents to enhance activity of Pseudozyma antarctica lipase B towards ortho-substituted 1-phenylethanols

Pseudozyma (Candida) antarctica lipase B (CAL-B, Novozym 435) is one of the most widely used and outstanding biocatalysts. However, CAL-B-catalyzed transesterification of ortho-substituted 1-phenylethanol analogs suffers low conversion. In this research, the reactions were accelerated by using CO2-expanded liquids, liquids expanded by dissolving pressurized CO2, such as CO2-expanded hexane or CO2-expanded MeTHF.

Chemical modification of lipase for rational enhancement of enantioselectivity

Chemical modifications of the I287C mutant of a Burkholderia cepacia lipase afforded various I287C-X conjugates, among which I287C-PAA bearing an N-phenylacetamide (PAA) moiety showed excellent enantioselectivity and catalytic activity for secondary alcohols. Site-directed chemical modifications are powerful tools to control enantioselective biocatalysis.

Dynamic kinetic resolution of a wide range of secondary alcohols: Cooperation of dicarbonylchlorido(pentabenzylcyclopentadienyl)ruthenium and CAL-B

The substrate scope in the dynamic kinetic resolution ofsecondary alcohols was studied by using 31 structurallydifferent alcohols and isopropenyl acetate in the presence ofdicarbonylchlorido(pentabenzylcyclopentadienyl)rutheniumand Candida antarctica lipase B (Novozym 435, CAL-B) in toluene. The enzyme and the ruthenium complex were shown to function in a highly compatible manner allowing the conversion of the racemic alcohols into the (R)-acetates in practically theoretical yields and, in most cases, ee values exceeding 99%. The results are fully comparable to those published previously by using earlier reported, state-of-the-art ruthenium-based catalysts for the alcohol racemization. A clear benefit of the dicarbonylchlorido(pentabenzylcyclopentadienyl)ruthenium system, when compared to other (cyclopentadienyl)ruthenium racemization catalysts, is its simple and cost-efficient preparation. The substrate scope of 31 secondary alcohols was studied in the dynamic kinetic resolution by utilizing dicarbonylchlorido(pentabenzylcyclopentadienyl)rutheniumand Candida antarctica lipase B (CAL-B) in the acylation with isopropenyl acetate in toluene at room temperature. The secondary alcohols were transformed into highly enantiopure (R)-acetates (in most cases ee > 99%) in close to quantitative isolatedyields. Copyright

Immobilized Manihot esculenta preparation as a novel biocatalyst in the enantioselective acetylation of racemic alcohols

The enzymatic preparation obtained from a discard of Manihot esculenta roots has been successfully immobilized on calcium alginate hydrogels. This preparation has been tested as a chiral biocatalyst in the enzymatic acylation of a set of racemic aromatic alcohols. Depending on the reaction conditions, excellent enantioselectivities can be achieved. Some parameters that can alter the biocatalytic properties of the enzyme, such as solvent, temperature, acyl donor and substrate structure have been studied exhaustively in order to establish a deeper knowledge of this novel biocatalyst.

Asymmetric allylic alkylation catalyzed by palladium complexes with a new chiral bisphosphine ligand

A novel, chiral bisphosphine ligand has been synthesized and its palladium complexes have been used in asymmetric allylic alkylation. High reactivity and moderate selectivity have been realized in the reaction between 1,3-diphenyl-2-propenyl acetate and dimethyl malonate.