187866-73-5Relevant articles and documents
DPT-mediated synthesis of 2-aminoimidazolidin-4-ones from thioureas tethered to amides
Bepary, Sukumar,Youn, In Kwon,Lim, Hee-Jong,Lee, Ge Hyeong
supporting information, p. 1876 - 1880 (2014/07/07)
2-Aminoimidazolidin-4-ones have been synthesized by using di-2-pyridyl thiocarbonate (DPT), taking the thioureas tethered to amides as the starting materials. Both the primary amides and secondary amides have been subjected to this cyclization method and
Effects of 2-(substituted-sulfanyl)-3,5-dihydro-imidazole-4-one and 2-(Substituted-sulfanyl)-1H-imidazole-4,5-dione derivatives on serum HDL-cholesterol
Elokdah, Hassan,Sulkowski, Theodore,Cochran, David,McKean, Mar-Lee,Quinet, Elaine
, p. 1791 - 1794 (2007/10/03)
A series of 2-substituted sulfanyl-3,5-dihydro-imidazole-4-ones and 2-substituted sulfanyl-1H-imidazole-4,5-diones was prepared and shown to increase high density lipoprotein cholesterol over other lipid fractions. Compound 1f showed efficacy in additional animal models. The major metabolite of 1f was isolated and its synthesis is reported. The effects of the metabolite on the lipid profile in rats were investigated. (C) 2000 Elsevier Science Ltd. All rights reserved.
2-(substituted sulfanyl)-3,5-dihydro-imidazol-4-one derivatives for increasing HDL cholesterol levels
-
, (2008/06/13)
A method for increasing blood serum HDL cholesterol levels in a mammal in need of increased HDL cholesterol blood serum levels, which comprises administering to said mammal, an effective amount of a compound of formula I: STR1 wherein R is phenyl or pheny
