187870-78-6 Usage
Description
Rimeporide, also known as EMD-87580, is a pharmaceutical compound that functions as a selective and potent inhibitor of the sodium-hydrogen antiporter 1 (NHE-1). It is primarily used in the field of cardiology to study its effects on the hypertrophic response in cardiac ventricular myocytes.
Uses
Used in Cardiology:
Rimeporide is used as a selective and potent NHE-1 inhibitor for studying its effects on the hypertrophic response in cardiac ventricular myocytes. This application is crucial in understanding the role of NHE-1 in cardiac hypertrophy and potentially developing treatments for related conditions.
Biochem/physiol Actions
EMD-87580 is a selective inhibitor of the Na+/H+ exchanger subtype 1 (NHE-1), also known as the Na+/H+ antiporter. EMD-87580 has shown cardioprotective effects, and has been investigated as a possible treatment for Duchenne′s muscular dystrophy.
Check Digit Verification of cas no
The CAS Registry Mumber 187870-78-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,8,7 and 0 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 187870-78:
(8*1)+(7*8)+(6*7)+(5*8)+(4*7)+(3*0)+(2*7)+(1*8)=196
196 % 10 = 6
So 187870-78-6 is a valid CAS Registry Number.