187930-97-8Relevant academic research and scientific papers
An Enantioselective Synthesis of (-)-Nonactic Acid and (+)-8-epi-Nonactic Acid Using Microbial Reduction
Takatori, Kazuhiko,Tanaka, Kenji,Matsuoka, Katsunori,Morishita, Kazuyoshi,Kajiwara, Masahiro
, p. 159 - 160 (1997)
An enantioselective synthesis of (-)-nonactic acid (2a) and (+)-8-epi-nonactic acid (2b) is described. The microbial reduction of the dl-ketone 3 with baker's yeast gave two easily separable diastereomeric alcohols 11a and 11b, each in over 97% ee. These alcohols were converted to 2a and 2b in 4 steps.
