187940-01-8

Basic information

• Product Name: 1-(4'-bromophenyl)-6,7-dimethoxyisochroman
• Synonyms: 1-(4'-bromophenyl)-6,7-dimethoxyisochroman
• CAS NO: 187940-01-8
• Molecular Weight: 349.224
• Mol File: 187940-01-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(4'-bromophenyl)-6,7-dimethoxyisochroman(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4'-bromophenyl)-6,7-dimethoxyisochroman(187940-01-8)
• EPA Substance Registry System: 1-(4'-bromophenyl)-6,7-dimethoxyisochroman(187940-01-8)

Safety Data

• Hazardous Substances Data: 187940-01-8(Hazardous Substances Data)

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 
• 7417-21-2 2-(3,4-dimethoxyphenyl)ethyl alcohol 

Downstream Products

• 213385-73-0 1-(4-bromo-phenyl)-7,8-dimethoxy-3,5-dihydro-benzo[d][1,2]diazepine-4-thione 
• 187940-20-1 1-(4-bromophenyl)-7,8-dimethoxy-3-methyl-3,5-dihydro-4H-2,3-benzodiazepin-4-one 
• 187940-09-6 1-(4-Bromo-phenyl)-7,8-dimethoxy-3,5-dihydro-benzo[d][1,2]diazepin-4-one 
• 187940-03-0 [2-(4-Bromo-benzoyl)-4,5-dimethoxy-phenyl]-acetic acid 

Relevant articles and documents

Heteropolyacid ionic liquid heterogeneously catalyzed synthesis of isochromansviaoxa-Pictet-Spengler cyclization in dimethyl carbonate

A recyclable and efficient heterogeneous, green catalyst based on the synthesis of Keggin-type polyoxometalate (H3PMo12O40) and vitamin B1 analogue 3-ethyl-5-(2-hydroxyethyl)-4-methylthiazol-3-ium (HEMT),i.e., [HEMTH]H2[PMo12O40] was prepared. Oxa-Pictet-Spengler cyclization of arylethanols and aldehydes were catalyzed to afford various substituted isochromans in moderate conditions with excellent yields using dimethyl carbonate (DMC) as a green solvent. Furthermore, this protocol was applicable in a gram-scale reaction, and the catalyst could be recycled eight times without significant loss of activity.

Design and development of 2,3-benzodiazepine (CFM) noncompetitive AMPA receptor antagonists

2,3-Benzodiazepines represent a class of heterocyclic compounds that interact with AMPA-type glutamate receptors in a noncompetitive manner. These compounds have attracted great interest for their pharmacological effects against acute and chronic neurodeg