187942-11-6

Basic information

• Product Name: 5,8-dichloro-3-(4-chlorophenyl)[1,2,4]triazolo[4,3-c]quinazoline
• CAS NO: 187942-11-6
• Molecular Weight: 349.606
• Mol File: 187942-11-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5,8-dichloro-3-(4-chlorophenyl)[1,2,4]triazolo[4,3-c]quinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 5,8-dichloro-3-(4-chlorophenyl)[1,2,4]triazolo[4,3-c]quinazoline(187942-11-6)
• EPA Substance Registry System: 5,8-dichloro-3-(4-chlorophenyl)[1,2,4]triazolo[4,3-c]quinazoline(187942-11-6)

Safety Data

• Hazardous Substances Data: 187942-11-6(Hazardous Substances Data)

Upstream product

• 6625-94-1 2,4,7-trichloroquinazoline 
• 122-01-0 4-chloro-benzoyl chloride 
• 187942-10-5 (2,7-dichloroquinazolin-4-yl) hydrazine 

Relevant articles and documents

Fused pyrimidines. Synthesis of new derivatives of potential diuretic activity

Certain derivatives of quinazoline and its bioisostere pyridopyrimidine carrying important structural features that contribute to diuretic activity, such as sulfonamido, morpholino and chlorophenyl, were prepared as potential diuretic agents. Likewise, some tricyclic 1,2,4-triazolo[3,4-b]quinazolins and pyrido[3,2-d][1,2,4]triazolo[4,3-a] pyrimidines with the same features were reported. Nine compounds were tested for the diuretic activity in rats and the results showed that the active compounds is 7-chloro-2-methyl-3-phthalimido-4(3H)-quinazoline.