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Acetylcorynoline, with the molecular formula C21H23NO5, is a natural product derived from the plant Corydalis turtschaninovii Besser. It is a member of the isoquinoline alkaloids family and is known for its diverse pharmacological activities, such as neuroprotection, anti-inflammation, and anti-tumor effects. ACETYLCORYNOLINE(P)'s ability to modulate key molecular targets like the nuclear factor-κB (NF-κB) pathway and the mitogen-activated protein kinase (MAPK) signaling pathway has positioned it as a promising drug candidate for treating various diseases, including cancer and neurodegenerative disorders.

18797-80-3

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18797-80-3 Usage

Uses

Used in Pharmaceutical Industry:
Acetylcorynoline is used as a neuroprotective agent for its potential to protect neurons from damage and degeneration, which is particularly relevant for the treatment of neurodegenerative disorders.
Used in Oncology:
In the field of oncology, Acetylcorynoline is used as an anti-tumor agent due to its ability to inhibit tumor growth and progression by modulating molecular targets within the NF-κB and MAPK signaling pathways.
Used in Anti-Inflammatory Applications:
Acetylcorynoline is utilized as an anti-inflammatory agent, leveraging its capacity to reduce inflammation, which can be beneficial in treating conditions characterized by excessive or chronic inflammation.
Used in Drug Development:
As a promising drug candidate, Acetylcorynoline is used in the development of new therapeutics aimed at various diseases, capitalizing on its multifaceted pharmacological profile to address unmet medical needs.

Check Digit Verification of cas no

The CAS Registry Mumber 18797-80-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,7,9 and 7 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 18797-80:
(7*1)+(6*8)+(5*7)+(4*9)+(3*7)+(2*8)+(1*0)=163
163 % 10 = 3
So 18797-80-3 is a valid CAS Registry Number.
InChI:InChI=1/C23H23NO6/c1-12(25)30-20-7-13-6-18-19(28-10-27-18)8-14(13)22-23(20,2)16-4-5-17-21(29-11-26-17)15(16)9-24(22)3/h4-6,8,20,22H,7,9-11H2,1-3H3/t20-,22+,23-/m0/s1

18797-80-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Acetylcorynoline

1.2 Other means of identification

Product number -
Other names O-acetyl-13-methyl-chelidonine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18797-80-3 SDS

18797-80-3Downstream Products

18797-80-3Relevant academic research and scientific papers

A BIOMIMETIC SYNTHESIS OF -CORYNOLINE, -11-EPICORYNOLINE, -ISOCORYNOLINE, AND -EPIISOCORYNOLINE FROM CORYSAMINE

Hanaoka, Miyoji,Yoshida, Shuji,Mukai, Chisato

, p. 6621 - 6624 (2007/10/02)

A novel and efficient synthesis of hexahydrobenzophenanthridine alkaloids, -corynoline, -11-epicorynoline, -isocorynoline, and -11-epiisocorynoline was accomplished from protoberberine alkaloid, corysamine through a biogenetic route.

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