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Corysamine chloride, also known as Berbinium or by its chemical descriptor 7,8,13,13a-tetradehydro-13-methyl-2,3:9,10-bis(methylenedioxy)- (8CI), is a protoberberine alkaloid that serves as a key intermediate in the biomimetic synthesis of hexahydrobenzo[c]phenanthridine alkaloids such as corynoline, epicorynoline, isocorynoline, and epiisocorynoline. Its structural features enable efficient transformation into these target compounds through oxidative and reductive steps, highlighting its utility as a precursor in synthetic alkaloid chemistry.

30243-28-8

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30243-28-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 30243-28-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,2,4 and 3 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 30243-28:
(7*3)+(6*0)+(5*2)+(4*4)+(3*3)+(2*2)+(1*8)=68
68 % 10 = 8
So 30243-28-8 is a valid CAS Registry Number.
InChI:InChI=1/C20H16NO4/c1-11-13-2-3-16-20(25-10-22-16)15(13)8-21-5-4-12-6-17-18(24-9-23-17)7-14(12)19(11)21/h2-3,6-8H,4-5,9-10H2,1H3/q+1

30243-28-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 13-methyl-6,7-dihydro-[1,3]dioxolo[4,5-g][1,3]dioxolo[4',5':7,8]isoquino[3,2-a]isoquinolinylium

1.2 Other means of identification

Product number -
Other names 13-methyl-coptisinium

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:30243-28-8 SDS

30243-28-8Relevant articles and documents

A General, Concise Strategy that Enables Collective Total Syntheses of over 50 Protoberberine and Five Aporhoeadane Alkaloids within Four to Eight Steps

Zhou, Shiqiang,Tong, Rongbiao

supporting information, p. 7084 - 7089 (2016/05/19)

A concise, catalytic, and general strategy that allowed efficient total syntheses of 22 natural 13-methylprotoberberines within four steps for each molecule is reported. This synthesis represents the most efficient and shortest route to date, featuring three catalytic processes: CuI-catalyzed redox-A3 reaction, Pd-catalyzed reductive carbocyclization, and PtO2-catalyzed hydrogenation. Importantly, this new strategy to the tetracyclic framework has also been applied to the collective concise syntheses of >30 natural protoberberines (without 13-methyl group) and five aporhoeadane alkaloids.

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