187979-52-8

Basic information

• Product Name: D-myo-Inositol, 3-O-(4-methoxyphenyl)methyl-2,4,5,6-tetrakis-O-(phenylmethyl)-
• Synonyms: D-myo-Inositol, 3-O-(4-methoxyphenyl)methyl-2,4,5,6-tetrakis-O-(phenylmethyl)-
• CAS NO: 187979-52-8
• Molecular Formula: C₄₂H₄₄O₇
• Molecular Weight: 660.79
• Mol File: 187979-52-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: D-myo-Inositol, 3-O-(4-methoxyphenyl)methyl-2,4,5,6-tetrakis-O-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: D-myo-Inositol, 3-O-(4-methoxyphenyl)methyl-2,4,5,6-tetrakis-O-(phenylmethyl)-(187979-52-8)
• EPA Substance Registry System: D-myo-Inositol, 3-O-(4-methoxyphenyl)methyl-2,4,5,6-tetrakis-O-(phenylmethyl)-(187979-52-8)

Safety Data

• Hazardous Substances Data: 187979-52-8(Hazardous Substances Data)

Upstream product

• 6404-82-6 (+/-)-1,2-O-isopropylidene-myo-inositol 
• 187841-22-1 1D-1-O-allyl-2,4,5,6-tetra-O-benzyl-3-O-p-methoxybenzyl-myo-inositol 
• 226889-48-1 (1S,2S,3R,4S,5S,6S)-3,4,6-Tris-benzyloxy-5-(4-methoxy-benzyloxy)-cyclohexane-1,2-diol 
• 187979-53-9 (3aR,4S,5R,6S,7S,7aR)-5-Allyloxy-4,6-bis-benzyloxy-7-(4-methoxy-benzyloxy)-2,2-dimethyl-hexahydro-benzo[1,3]dioxole 
• 187979-44-8 (1S,2S,3R,4S,5R,6R)-4-Allyloxy-3,5-bis-benzyloxy-6-(4-methoxy-benzyloxy)-cyclohexane-1,2-diol 
• 187979-42-6 (3aR,4S,5R,6S,7S,7aR)-4,6-Bis-benzyloxy-7-(4-methoxy-benzyloxy)-2,2-dimethyl-hexahydro-benzo[1,3]dioxol-5-ol 
• 824-94-2 p-methoxybenzyl chloride 
• 140887-04-3 (+/-)-2,5,6-Tri-O-benzyl-3,4-O-isopropylidene-1-O-p-methoxybenzyl-myo-inositol 
• 100-39-0 benzyl bromide 
• 140887-09-8 (1R,2R,3S,4R,5R,6R)-2,3,4,6-Tetrakis-benzyloxy-5-(4-methoxy-benzyloxy)-cyclohexanol 
• 141040-63-3 2,4,5,6-tetra-O-benzyl-DL-myo-inositol 
• 129952-31-4 (+/-)-2,4,6-tri-O-benzyl-1,3-O-methylidene-D-myo-inositol 

Downstream Products

• 26277-05-4 1,2,4,5,6-penta-O-benzyl-sn-myo-inositol 

Relevant articles and documents

General synthesis of 3-phosphorylated mj'o-inositol phospholipids and derivatives

The D-3-phosphorylated wyo-inositol phospholipids PtdIns(3)P, PtdIns(3,4)P2, PtdIns(3,4,5)P3 and PtdIns(3,5)P2 were synthesised from /yo-inositol orthoformate 8. Key transformations included the regioselective DIBAL- and trimethylaluminium-mediated cleavages of wiyo-inositol orthoformate intermediates and a resolution-protection protocol using the camphor acetals 17. The final reductive debenzylation was effected with Pearlman's catalyst [Pd(OH)J in the presence of sodium hydrogen carbonate. The biological properties of the phospholipids were evaluated against various protein kinases (PKB and PDK-1) in which they played an important activation role.