188004-31-1Relevant articles and documents
A steric control of regioselectivity in palladium-catalyzed cyclizations of alkenes bearing arylbromides and nucleophiles
Bruyere, Didier,Gaignard, Gaelle,Bouyssi, Didier,Balme, Genevieve,Lancelin, Jean-Marc
, p. 827 - 830 (1997)
The stereocontrolled synthesis of tricyclic compounds through an efficient and highly regioselective 5-exo-trig palladium catalyzed biscyclization process is reported, starting from compounds 1. The 6-endo competing cyclization can also be the only pathwa
Intramolecular Pd-catalyzed carboetherification and carboamination. Influence of catalyst structure on reaction mechanism and product stereochemistry
Nakhla, Josephine S.,Kampf, Jeff W.,Wolfe, John P.
, p. 2893 - 2901 (2007/10/03)
The intramolecular Pd-catalyzed carboetherification of alkenes affords 2-indan-1-yltetrahydrofuran products in moderate to good yield with good to excellent levels of diastereoselectivity. The stereochemical outcome of these reactions is dependent on the
A study on the regio- and stereoselectivity in palladium-catalyzed cyclizations of alkenes and alkynes bearing bromoaryl and nucleophilic groups
Bruyère, Didier,Bouyssi, Didier,Balme, Geneviève
, p. 4007 - 4017 (2007/10/03)
We have studied the remarkable dependence of the stereochemistry of the cyclization on the double bond geometry and of the effect of the bulkiness of the nucleophile on the regiochemistry of the palladium mediated cyclization of alkenes bearing aryl bromides and nucleophiles. In contrast, the cyclization of the acetylenic homologous substrates is not dependent on the nature of the nucleophile.