188118-73-2

Upstream product

• 188118-61-8 Acetic acid (1S,4R)-4-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-cyclopent-2-enylmethyl ester 
• 143395-28-2 (1R,5R)-5-hydroxymethyl-2-cyclopenten-1-ol 
• 148473-12-5 (1R,5S,1'S)-5-(1',2'-Dihydroxyethyl)cyclopent-2-en-1-ol 
• 216441-13-3 (1S,2R)-2-Hydroxy-cyclopent-3-enecarbaldehyde 
• 178456-34-3 (1R,2R)-2-acetoxy-1-(acetoxymethyl)-3-cyclopentene 
• 160154-62-1 (S)-2-Acetoxy-propionic acid (3S,3aS,6aR)-2-oxo-3,3a,4,6a-tetrahydro-2H-cyclopenta[b]furan-3-yl ester 

Downstream Products

• 180088-49-7 4-Amino-1-[(1R,2S,3R,4R)-4-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-2-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-cyclopentyl]-1H-pyrimidin-2-one 
• 71184-20-8 D-(-)-carbodine 

Relevant academic research and scientific papers

Synthesis and incorporation of carbocyclic nucleosides into a hammerhead ribozyme domain-RNase resistance and catalytic activity

A hammerhead ribozyme domain incorporating (-)-carbodine 8a and (-)-aristeromycin 8b at selected positions, manifests increased RNase resistance and exhibits significant catalytic activity.

An expeditious route to carbocyclic nucleosides: (-)-Aristeromycin and (-)-carbodine

The readily available bicyclic lactone (-)-1 was transformed into diacetate (-)-2 which served in an expeditious route to (-)-aristeromycin (3a) and (-)-carbodine (3b) in acceptable yields.