Synthesis and incorporation of carbocyclic nucleosides into a hammerhead ribozyme domain-RNase resistance and catalytic activity

DOI: 10.1039/CC9960001623

Source and publish data:

Chemical Communications p. 1623 - 1624 (1996)

Update date:2022-08-03

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Authors:

Burlina, Fabienne

Favre, Alain

Fourrey, Jean-Louis

Thomas, Martial

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Article abstract of DOI:10.1039/CC9960001623

A hammerhead ribozyme domain incorporating (-)-carbodine 8a and (-)-aristeromycin 8b at selected positions, manifests increased RNase resistance and exhibits significant catalytic activity.

Full text of DOI:10.1039/CC9960001623

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