188174-23-4

Usage

Uses

Used in Pharmaceutical Industry:
(2-amino-4,5-dimethoxyphenyl)methanol is used as a key intermediate in the synthesis of various pharmaceuticals and organic compounds. Its unique structure and functional groups make it a valuable component in the development of new drugs and pharmacological agents.
Used in Medicinal Chemistry Research:
(2-amino-4,5-dimethoxyphenyl)methanol is used as a versatile building block for the synthesis of biologically active molecules. Its structural features and functional groups enable the creation of diverse compounds with potential therapeutic applications.
Used in Drug Development:
(2-amino-4,5-dimethoxyphenyl)methanol is used as a starting material in the development of new drugs and pharmacological agents. Its potential physiological effects and interactions with biological systems make it a promising candidate for further investigation and research in the field of medicinal chemistry.

Upstream product

• 1016-58-6 6-nitroveratryl alcohol 
• 20357-25-9 6-nitroveratraldehyde 
• 26759-46-6 methyl 2-amino-4,5-dimethoxybenzoate 

Downstream Products

• 197525-02-3 2-azido-4,5-(dimethoxy)benzyl alcohol 
• 22608-87-3 2-amino-4,5-dimethoxybenzaldehyde 
• 871563-17-6 N-(2-hydroxymethyl-4,5-dimethoxyphenyl)-4-methylbenzenesulfonamide 
• 886499-20-3 N-(2-formyl-4,5-dimethoxyphenyl)-4-methylbenzenesulfonamide 
• 57179-07-4 6,7-dimethoxy-2-phenylquinoline 

Relevant academic research and scientific papers

Iron-catalyzed cascade reaction of 2-aminobenzyl alcohols with benzylamines: Synthesis of quinazolines by trapping of ammonia

A novel approach to construct 2-aryl/heteroaryl quinazolines was developed through an iron-catalyzed cascade reaction of 2-aminobenzyl alcohols with benzylamines under aerobic oxidative conditions. The reaction proceeds via the formation of N-benzylideneb

Sunlight-Driven Forging of Amide/Ester Bonds from Three Independent Components: An Approach to Carbamates

A photoredox catalytic route to carbamates enabled by visible irradiation (or simply sunlight) has been developed. This process leads to a novel approach to the construction of heterocyclic rings wherein the amide or ester motifs of carbamates were assembled from three isolated components. Large-scale experiments were realized by employing continuous flow techniques, and reuse of photocatalyst demonstrated the green and sustainable aspects of this method.

Synthesis of polysubstituted cyclopenta[b]indoles via relay gold(i)/Bronsted acid catalysis

An efficient relay catalytic process involving Au(i)/Bronsted acid to access various polysubstituted cyclopentannulated indoles from easily accessible 1-(2-aminophenyl)prop-2-ynols and readily available 1,3-dicarbonyls has been developed. In an unprecedented event, the intermediate 2-indolylmethyl cations undergo the cation-Ene reaction with various 1,3-dicarbonyls followed by an intramolecular Friedel-Crafts-type reaction generating functionalized cyclopenta[b]indoles. This journal is

Synthesis of 1-acyl-3,4-dihydroquinazoline-2(1H)-thiones by cyclization of N-[2-(isothiocyanatomethyl)phenyl] amides generated in situ from N-[2-(azidomethyl)phenyl] amides

An efficient method for the preparation of 1-acyl-3,4-dihydroquinazoline- 2(1H)-thiones 5 has been developed. The reaction of N-[2-(azidomethyl)phenyl] amides 3, easily prepared by a three-step sequence starting with (2-aminophenyl)methanols, with Ph

Intramolecular [2 + 2] cycloaddition of ketenimines with imines. Synthesis and chemical behaviour of azeto[2,1-b]quinazolines

Azeto[2,1-b]quinazolines 5 have been prepared by the novel intramolecular [2 + 2] cycloaddition reaction of ketenimines with imines. The applicability and limitations of the synthetic methodology, and explorations on the reactivity of compounds 5 are discussed.