188184-69-2Relevant academic research and scientific papers
A chemo-enzymatic synthesis of the N-terminal aminoacid lactone of Nikkomycin B
Kapeller,Jary,Hayden,Griengl
, p. 245 - 251 (1997)
(2S,3S,4S)-4-(4-Acetoxyphenyl)-2-amino-3-methylbutan-4-olide (S,S,S)-11, a precursor for the aminoacid part of Nikkomycin B, was prepared in a five step synthesis in 12% yield, involving two enzymatic steps. First enantiopurity was achieved by resolution
