188304-72-5Relevant articles and documents
Rational design, synthesis, and reactivity of lactendiynes, a new class of cyclic enediynes ortho-fused with the β-lactam ring
Banfi, Luca,Basso, Andrea,Guanti, Giuseppe
, p. 3249 - 3268 (1997)
A series of 10-membered cyclic enediynes trans-fused with N-protected and N-unprotected β-lactams have been stereoselectively prepared. These compounds were found to be stable toward Bergman cycloaramatization, which, an the other hand, takes place readily when the azetidinone ring is opened.