188399-78-2Relevant academic research and scientific papers
The synthesis of enantiomerically pure, symmetrically substituted cyclopropane phosphonic acids - a constrained analog of the GABA antagonist phaclophen
Hanessian, Stephen,Cantin, Louis-David,Roy, Stephan,Andreotti, Daniele,Gomtsyan, Arthur
, p. 1103 - 1106 (2007/10/03)
The stereocontrolled conjugate addition of anions derived from chiral α-chlorophosphonamides to α,β-unsaturated esters leads to the corresponding 3-chloro ester adducts which undergo intramolecular expulsion of the chlorine atom to give the corresponding cyclopropanes.
