1884-88-4 Usage
Uses
Used in Organic Synthesis:
(1S,2S)-2-amino-1-(4-nitrophenyl)-3-(triphenylmethoxy)propan-1-ol is used as a building block in organic synthesis for the creation of complex organic molecules. Its chiral nature allows for asymmetric synthesis, which is crucial for producing enantiomerically pure compounds with specific biological activities.
Used in Biochemical Research:
In biochemical research, (1S,2S)-2-amino-1-(4-nitrophenyl)-3-(triphenylmethoxy)propan-1-ol serves as a valuable tool for studying enzyme mechanisms, receptor interactions, and other biological processes. Its functional groups can be modified or used as starting points for the development of new biochemical probes and assays.
Used in Pharmaceutical Development:
Due to the presence of the amino and nitro groups, (1S,2S)-2-amino-1-(4-nitrophenyl)-3-(triphenylmethoxy)propan-1-ol has potential as a pharmacological agent. It can be further modified or used as a precursor in the development of new drugs with specific therapeutic targets and applications.
Used in Chiral Compound Synthesis:
The chiral nature of (1S,2S)-2-amino-1-(4-nitrophenyl)-3-(triphenylmethoxy)propan-1-ol makes it an ideal candidate for the synthesis of other chiral compounds. These compounds are essential in various industries, including pharmaceuticals, agrochemicals, and materials science, where enantioselectivity is crucial for desired biological activity and to avoid unwanted side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 1884-88-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,8 and 4 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1884-88:
(6*1)+(5*8)+(4*8)+(3*4)+(2*8)+(1*8)=114
114 % 10 = 4
So 1884-88-4 is a valid CAS Registry Number.
1884-88-4Relevant academic research and scientific papers
Synthetic studies on d-biotin. Part 7: A practical asymmetric total synthesis of d-biotin via enantioselective reduction of meso-cyclic imide catalyzed by oxazborolidine
Chen, Fen-Er,Dai, Hui-Fang,Kuang, Yun-Yan,Jia, Hui-Qing
, p. 3667 - 3672 (2007/10/03)
A novel and convenient method for the stereoselective synthesis of d-biotin 1 starting from the commercially available cis-1,3-dibenzyl-2- imidazolidone-4,5-dicarboxylic acid 2 has been developed. The key features of this synthesis include the enantioselective reduction of a meso-cyclic imide, mediated by a chiral oxazborolidine catalyst, derived from (1S,2S)-(+)-threo-1- (4-nitrophenyl)-2-amino-1,3-propanediol and the direct introduction of a C 5 side chain to the (3aS,6aR)-thiolactone through a modified di-Grignard reaction. Enantioselectivities of 98% in the oxazborolidine- catalyzed asymmetric reduction process have been achieved.
