188401-92-5

Upstream product

• 126550-74-1 (2R,5S)-1-tert-butoxycarbonyl-2-benzyloxymethyl-5-benzyloxymethylpyrrolidine 
• 100-39-0 benzyl bromide 
• 1374604-66-6 (2S,5S)-N-benzyl-2,5-bis(benzyloxymethyl)pyrrolidine 
• 253776-40-8 (2R,5S)-3-Benzenesulfonyl-2,5-bis-benzyloxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 175229-12-6 (R)-3-benzyloxy-2-(tert-butoxycarbonylamino)propyl phenyl sulfone 

Downstream Products

• 1353017-30-7 (2S,5S)-N,N'-dimethyl-2,5-bis(benzyloxymethyl)pyrrolidinium iodide 

Relevant academic research and scientific papers

C2-symmetric pyrrolidine-based chiral ammonium salts as a phase-transfer catalyst

Chiral pyrrolidinium salts having substituents at the α, α' positions were synthesized to develop a chiral phase-transfer catalyst which have more simplified structure. The catalytic function of these synthesized catalysts was evaluated using asymmetric b

A straightforward synthesis of enantiomerically pure trans-2,5-bis(alkyloxymethyl) pyrrolidines by 1,3-dipolar cycloaddition reactions of azomethine ylides

A new efficient method for the stereoselective preparation of trans-2,5-bis(alkyloxymethyl)pyrrolidines (7) using easily available starting materials is described. The main step of this synthesis is the stereoselective formation of the pyrrolidine ring by

Versatile synthesis of enantiomerically pure trans-2,5-disubstituted pyrrolidines

Enantiomerically pure trans-(2S,5S)-2,5-disubstituted pyrrolidine was synthesized starting from the versatile chiral synthon (R)-(8) and chiral 2,3-O-isopropylideneglycerol triflate (S)-(9).