1885-77-4

Basic information

• Product Name: 3-CYANO-2-NITROTOLUENE
• Synonyms: 3-CYANO-2-NITROTOLUENE;3-METHYL-2-NITRO-BENZONITRILE
• CAS NO: 1885-77-4
• Molecular Formula: C₈H₆N₂O₂
• Molecular Weight: 162.15
• EINECS: 604-604-1
• Mol File: 1885-77-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-CYANO-2-NITROTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CYANO-2-NITROTOLUENE(1885-77-4)
• EPA Substance Registry System: 3-CYANO-2-NITROTOLUENE(1885-77-4)

Safety Data

• Hazardous Substances Data: 1885-77-4(Hazardous Substances Data)

Upstream product

• 5437-38-7 3-methyl-2-nitrobenzoic acid 
• 60310-07-8 3-Methyl-2-nitrobenzenecarboxamide 
• 7719-09-7 thionyl chloride 
• 7664-93-9 sulfuric acid 
• 620-22-4 3-Methylbenzonitrile 

Downstream Products

• 1261498-74-1 3-(bromomethyl)-2-nitrobenzonitrile 
• 1380316-35-7 ethyl 3-cyano-N-(diphenylmethylene)-2-nitrophenylalaninate 
• 1427420-64-1 C₂₀H₂₁NO₅S 
• 108078-14-4 2-iodo-3-methylbenzoic acid 
• 52107-93-4 2-iodo-3-methylbenzoyl chloride 
• 52107-79-6 1-(2-iodo-3-methylphenyl)ethanone 
• 939970-68-0 2-mercapto-3-methylbenzonitrile 
• 939970-61-3 2-benzylsulfanyl-3-methylbenzonitrile 
• 1885-32-1 2-amino-3-methylbenzamide 
• 4389-45-1 3-methylantranilic acid 
• 69797-49-5 2-amino-3-methylbenzonitrile 
• 60310-07-8 3-Methyl-2-nitrobenzenecarboxamide 

Relevant articles and documents

KAT II INHIBITORS

The present invention relates to compounds 3-amino-1-hydroxy-2-oxo-1,2,3,4-tetrahydroquinoline-7-carbonitrile, 3-amino-1-hydxoxy-7-(2-methoxyethoxy)-3,4-dihydro-quinolin-2(1H)-one, and 3-amino-1-hydroxy-7-[(1S)-2-methoxy-1-methylethoxy]-3,4-dihydroquinolin-2(1H)-one, including racemic mixtures and resolved enantiomers thereof, to pharmaceutically acceptable salts thereof, and to the treatment of cognitive deficits associated with schizophrenia and other psychiatric, neurodegenerative and/or neurological disorders in mammals, including humans

Utilisation du cyanure de tetraethylammonium pour la preparation de complexes cyclopentadienyl fer cyclohexadienyl cyanes. Etude de leur oxydation electrochimique et chimique

Addition of tetraethylammonium cyanide to a solution of η5-cyclopentadienyl)(η6-arene)iron (1 +), in acetonitrile can be studied by voltammetry.With electron-withdrawing groups such as nitro, keto, sulfone, azo and azoxy bonded to the arene, the reaction occurs immediately and a wave resulting form oxidation of hexadienyl species is observed in the range 0-IV vs.SCE.Preparation of various hexadienyl compounds was achieved with good yields.In order to obtain ortho-substituted benzonitriles, electrochemical and chemical oxidations of hexadienyl complexes were compared.The best results were obtained with N-bromosuccinimide (NBS) and a demetallation generally occurs.A one-pot synthesis of benzonitrile compounds can be achieved after addition of cyanide ion and then NBS to a solution of (η5-cyclopentadienyl)(η6-arene) iron (1 +) in acetonitrile. 6-C6H5N(O)=NC6H4Cn-2>>+ is directly obtained from the azoxy dicationic compound 2+.Keywords: Iron; Ferrocenes; Electrochemistry; Arene complexes; Oxidation

N-SUBSTITUTED IMIDAZOLE AND BENZIMIDAZOLE DERIVATIVES USEFUL AS ANGIOTENSON II ANTAGONISTS

Compounds are disclosed having the formula STR1 These compounds inhibit the action of angiotensin II and are useful, therefore, for example, as antihypertensive agents.

Certain 1H-pyrrold[3,4-b]quinolin-1-one-9-amino-2,3-dihydro derivatives useful for treating anxiety

The present invention comprises certain quinoline lactams of formula I; pharmaceutically acceptable salts of the compounds of formula I; pharmaceutical compositions containing a compound of formula I, or a pharmaceutically acceptable salt thereof, for use in the treatment of anxiety; and processes for the manufacture of the compounds of formula I, as well as intermediates for use in such manufacture.