188532-49-2

Upstream product

• 82820-87-9 2,4-dibromobutanoyl chloride 
• 99-09-2 3-nitro-aniline 

Downstream Products

• 188533-76-8 (E)-(2R,6R,7R)-7-tert-Butoxycarbonylamino-3-[1-(3-nitro-phenyl)-2-oxo-pyrrolidin-3-ylidenemethyl]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-3-ene-2-carboxylic acid benzhydryl ester 
• 188535-42-4 (6R,7R)-7-tert-Butoxycarbonylamino-3-[1-(3-nitro-phenyl)-2-oxo-pyrrolidin-(3E)-ylidenemethyl]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 188534-23-8 (6R,7R)-7-tert-Butoxycarbonylamino-3-[1-(3-nitro-phenyl)-2-oxo-pyrrolidin-(3E)-ylidenemethyl]-5,8-dioxo-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 804555-02-0 (RS)-3-Bromo-1-(3-nitro-phenyl)-pyrrolidin-2-one 

Relevant academic research and scientific papers

Cephalosporin derivatives

The present invention relates to compounds of formula I STR1 wherein R1 is a group selected from 2-, 3-, and 4-hydroxyphenyl, 3-nitrophenyl, and 3-fluoro-4-hydroxyphenyl; as well as readily hydroyzable esters thereof, pharmaceutically acceptabl

Synthesis and structure-activity relationship of (lactamylvinyl)cephalosporins exhibiting activity against staphylococci, pneumococci, and enterococci

The synthesis and structure-activity relationships of a new class of vinylcephalosporins substituted with a lactamyl residue (1) are described. These compounds show excellent activity against enterococci and retain the broad spectrum activity of third-gen