82820-87-9

Usage

Uses

Used in Pharmaceutical Industry:
2,4-Dibromobutyryl chloride is used as a key intermediate for the synthesis of anti-inflammatory and analgesic agents. Its reactive bromine and acyl chloride groups facilitate the formation of new compounds with potential therapeutic properties.
Used in Chemical Synthesis:
2,4-Dibromobutyryl chloride is used as a reagent in the preparation of various organic compounds, such as methyl 2,4-dibromobutanoate and α-bromolactam. Its unique structure allows for the development of new molecules with diverse applications in different industries.
Used in Research and Development:
2,4-Dibromobutyryl chloride serves as a valuable building block in the development of new chemical entities and pharmaceuticals. Its versatility in reactions and ability to form stable intermediates make it an essential component in the synthesis of novel compounds with potential applications in various fields.

InChI:InChI=1/C4H5Br2ClO/c5-2-1-3(6)4(7)8/h3H,1-2H2

Upstream product

• 96-48-0 4-butanolide 
• 63164-16-9 2,4-dibromo-butyric acid 
• 927-58-2 4-bromobutyroyl chloride 

Downstream Products

• 93623-86-0 3-Bromo-1-{[1-phenyl-meth-(Z)-ylidene]-amino}-pyrrolidin-2-one 
• 77868-76-9 2,4-Dibromo-N-phenyl-butyramide 
• 105594-20-5 5-(2-Bromo-ethyl)-3-methyl-2-[(Z)-phenylimino]-thiazolidin-4-one 
• 77868-77-0 N-benzyl-2,4-dibromobutyramide 
• 111504-38-2 5-Phenylamino-4-thia-6-aza-spiro[2.4]hept-5-en-7-one 
• 111504-37-1 3-Phenyl-4-thioxo-3,5-diaza-tricyclo[5.2.2.0^1,5]undecane-2,6-dione 
• 111504-36-0 7-Bromo-3-phenyl-4-thioxo-3,5-diaza-tricyclo[5.2.2.0^1,5]undecane-2,6-dione 
• 111504-35-9 5-Benzylamino-4-thia-6-aza-spiro[2.4]hept-5-en-7-one 
• 111504-34-8 3-Benzyl-7-bromo-4-thioxo-3,5-diaza-tricyclo[5.2.2.0^1,5]undecane-2,6-dione 
• 111504-41-7 2-benzyl-6-bromo-8a-bromoethyl-2,3,7,8-tetrahydro-3-thioxoimidazo<1,5-a>pyridine-1,5(6H,8aH)-dione 
• 188532-59-4 (RS)-2,4-Dibromo-N-(3-methoxy-benzyl)-butyramide 
• 175917-50-7 carbonic acid (RS)-4-<(2,4-dibromobutyryl)amino>phenyl ester tert-butyl ester 
• 188532-49-2 (RS)-2,4-Dibromo-N-(3-nitro-phenyl)-butyramide 
• 188533-04-2 3-bromo-1-[(4-methoxyphenyl)methyl]pyrrolidin-2-one 

Relevant academic research and scientific papers

Method for preparing ceftobiprole analogues

The invention relates to a method for preparing a ceftobiprole analogue as shown in a formula VII.

5-Membered cyclic hydroxamic acids as HDAC inhibitors

The new histone deacylases inhibitors (HDACi) were synthesized in the class of 5-membered cyclic hydroxamic acids (5-CHA), showing medium size CHA as a new Zn-binding group. New reaction sequence was proposed for the synthesis of 5-membered alkylidene-cyc

Indium-mediated reductive dehalogenation of α-halocarbonyl compounds in water

Reactions of various α-halocarbonyl compounds 1 with indium in the presence of a catalytic amount of sodium dodecyl sulfate in water were performed to afford the corresponding parent carbonyl compounds 2 in excellent yields. The Royal Society of Chemistry 2000.

7-(2-Aminomethyl-1-azetidinyl)-4-oxoquinoline-3-carboxylic acids as potent antibacterial agents: Design, synthesis, and antibacterial activity

2-Aminomethyl-1-azetidinyl, -1-pyrrolidinyl, and -1-piperidinyl groups were designed as novel C-7 substituents for potential antibacterial quinolone agents. Of the three substituents, the 2-aminomethyl-1-azetidinyl group (compound 12a) was found to be the

Synthesis of β-enaminoesters and lactams by Michael addition of N- benzylaniline to new allenic esters and lactams

The synthesis of original allenic lactams 2 and allenic esters 5 is presented and their Michael condensation with N-benzylaniline described.

3-(3,5-di-tert-butyl-4-hydroxy benzylidene)-2-pyrrolidone and substituted derivatives thereof

3-(3,5-di-tert-butyl-4-hydroxy-benzylidene)-2-pyrrolidone and N-substituted derivatives thereof are described. The substituent includes alkyl, alkoxy, alkynyl phenyl-alkylene, hydroxy-alkylene and amino-alkylene. They are effective as an anti-inflammatory

Synthesis and antiinflammatory activities of 3-(3,5-di-tert-butyl-4-hydroxybenzylidene)pyrrolidin-2-ones

A series of 3-(3,5-di-tert-butyl-4-hydroxybenzylidene)pyrrolidin-2-ones was synthesized and evaluated as candidate antiinflammatory/analgesic agents as well as dual inhibitors of prostaglandin and leukotriene synthesis. Some compounds that showed dual inh

Preparations of Perhydroimidazopyridine-3-thiones and Thiazole-5-spirocyclopropan-4(5H)-ones from Thioureas and α,γ-Dibromobutyryl Chloride under Phase-transfer Conditions

The reaction of N-monosubstituted thioureas (1) with α,γ-dibromobutyryl chloride (2) was carried out in 5percent NaOH-CH2Cl2 to afford 2-alkyl(aryl)-6-bromo-2,3,7,8-tetrahydro-3-thioxo-6,8a-ethano-imidazopyridine-1,5(6H,8aH)-diones (3) and 2-alkyl(

Convenient Syntheses of Cyclic Carboxamides from α,β,γ,δ and ε-halocarboxamides under Phase Transfer Conditions

Piperazine-2,5-diones (2) were prepared by N-alkylation between two molecules of α-halocarboxamides (1) in the presence of a phase transfer catalyst in yields of 64-88percent. β,γ,δ and ε-Lactams (6,9 and 13) were similarly synthesized by intramolecular N-alkylation of the corresponding halocarboxamides (5, 8 and 12) under phase transfer conditions in 53-99percent yields.Keywords--piperazine-2,5-dione; β-lactam; γ, δ, and ε lactams; bis-β-lactam; phase transfer catalyst; intramolecular N-alkylation