188624-22-8Relevant academic research and scientific papers
Synthesis and Evaluation of Macrocyclic Peptide Aldehydes as Potent and Selective Inhibitors of the 20S Proteasome
Wilson, David L.,Meininger, Isabel,Strater, Zack,Steiner, Stephanie,Tomlin, Frederick,Wu, Julia,Jamali, Haya,Krappmann, Daniel,G?tz, Marion G.
, p. 250 - 255 (2016)
This research explores the first design and synthesis of macrocyclic peptide aldehydes as potent inhibitors of the 20S proteasome. Two novel macrocyclic peptide aldehydes based on the ring-size of the macrocyclic natural product TMC-95 were prepared and e
Chemoenzymatic synthesis of enantiomerically pure 4-fluoro-3-nitro and 3-fluoro-4-nitro phenylallanine
Vergne, Caroline,Bois-Choussy, Michele,Ouazzani, Jamal,Beugelmans, Rene,,Zhu, Jieping
, p. 391 - 398 (2007/10/03)
Both antipodes of enantiomerically pure 4-fluoro-3-nitrophenylalanine and 3-fluoro-4-nitrophenylalanine were obtained from their corresponding racemates via enzymatic resolution.
