370-54-7

Upstream product

• 188624-22-8 diethyl 2-acetamido-2-(3-fluoro-4-nitrobenzyl)malonate 
• 131858-37-2 4-(bromomethyl)-2-fluoro-1-nitrobenzene 
• 446-34-4 2-fluoro-4-methyl-1-nitrobenzene 

Downstream Products

• 188624-25-1 3-(3-Fluoro-4-nitro-phenyl)-2-(2,2,2-trifluoro-acetylamino)-propionic acid methyl ester 
• 188624-29-5 (S)-N-trifluoroacetyl-3-fluoro-4-nitrophenylalanine 
• 160247-85-8 (S)-3-fluoro-4-nitrophenylalanine methyl ester 

Relevant academic research and scientific papers

Synthesis and Evaluation of Macrocyclic Peptide Aldehydes as Potent and Selective Inhibitors of the 20S Proteasome

This research explores the first design and synthesis of macrocyclic peptide aldehydes as potent inhibitors of the 20S proteasome. Two novel macrocyclic peptide aldehydes based on the ring-size of the macrocyclic natural product TMC-95 were prepared and e

Chemoenzymatic synthesis of enantiomerically pure 4-fluoro-3-nitro and 3-fluoro-4-nitro phenylallanine

Both antipodes of enantiomerically pure 4-fluoro-3-nitrophenylalanine and 3-fluoro-4-nitrophenylalanine were obtained from their corresponding racemates via enzymatic resolution.