188656-21-5Relevant academic research and scientific papers
A convenient cross-coupling route to α,β,γ,δ-unsaturated amino acids
Burk, Mark J.,Allen, John G.,Kiesman, William F.,Stoffan, Karen M.
, p. 1309 - 1312 (1997)
β-Bromoenamide esters are coupled stereospecifically to vinylboronic acids via a palladium-catalyzed Suzuki reaction. This cross-coupling proceeds under mild conditions with Pd(OAc)2 in 95% EtOH at 50°C and produces amino acids with 1,3-diene side chains in high yields.
