A convenient cross-coupling route to α,β,γ,δ-unsaturated amino acids

DOI: 10.1016/S0040-4039(97)00065-8

Source and publish data:

Tetrahedron Letters p. 1309 - 1312 (1997)

Update date:2022-08-04

Topics:

Authors:

Burk, Mark J.

Allen, John G.

Kiesman, William F.

Stoffan, Karen M.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(97)00065-8

β-Bromoenamide esters are coupled stereospecifically to vinylboronic acids via a palladium-catalyzed Suzuki reaction. This cross-coupling proceeds under mild conditions with Pd(OAc)₂ in 95% EtOH at 50°C and produces amino acids with 1,3-diene side chains in high yields.

Full text of DOI:10.1016/S0040-4039(97)00065-8

Products guided by the article

Product name:2-Butenoic acid, 2-(acetylamino)-3-bromo-4-phenyl-, methyl ester, (E)-

Cas No:188656-21-5

R&D Labs maybe for 188656-21-5

Hebei Kangtai Pharmaceutical Co.,Ltd

Contact:+86-0317-3512963

Address:Wugang Road,Mengcun of Cangzhou City,Hebei Province ,China
HANGZHOU FOREWIN PHARMA CO., LTD

Contact:+86-571-89053961

Address:hangzhou
He Bei Shun Er Chemical Co., LTD.

Contact:86-0311-86996932/86860168

Address:No 18,North street
ShangHai Original Economy-Trade Develop Co.,Ltd.,

Contact:86-21-68552131

Address:shanghai
Shanghai Standard Biotech Co., Ltd.

Contact:+86-18502101150

Address:Room 103, Building 2nd, NO.720, Cailun Road , Pudong District, Shanghai, China

Relevant to this article

A turn-on fluorescent and colorimetric chemodosimeter for selective detection of Au³⁺ ions in solution and in live cells: Via Au³⁺-induced hydrolysis of a rhodamine-derived Schiff base

Doi:10.1039/d0nj01273d
(2020)
Configurational assignment of N-arylsulfonylimines of α- polychloroaldehydes

Doi:10.1002/mrc.2070
(2007)
Structure–Activity Relationships of WO_x-Promoted TiO₂–ZrO₂ Solid Acid Catalyst for Acetalization and Ketalization of Glycerol towards Biofuel Additives

Doi:10.1007/s10562-021-03733-2
(2021)
Synthesis and Reactivity of (1S,4S,5S)-5-Bromo-1,3,3-trimethyl-N-nitro-2-oxabicyclo<2.2.2>octan-6-imine. X-Ray Molecular Structure and Absolute Configuration of E and Z Isomers of (1S,4S)-5,5-Dibromo-1,3,3-trimethyl-N-nitro-2-oxabicyclo<2.2.2>octan-6-imin

Doi:10.1039/P19900003053
(1990)
Chemoenzymatic enantioselective synthesis of 7-azabicyclo[2.2.1]heptane derivatives

Doi:10.1016/j.tetasy.2011.05.016
(2011)
Synthesis and properties of partially fluorinated 4-alkyl-4′-cyanobiphenyls - Part II 4-alkyl-4′-cyano-2′3′5′6′-tetrafluorobiphenyls

Doi:10.1016/S0040-4020(01)87891-1
(1990)

Article Doi