18872-49-6Relevant academic research and scientific papers
Phosphorylation Organocatalysts Highly Active by Design
Dobrovetsky, Roman,Fallek, Amit,Kramer, Maria,Portnoy, Moshe,Weiss-Shtofman, Mor
supporting information, (2020/05/01)
The activity of nucleophilic organocatalysts for alcohol/phenol phosphorylation was enhanced through attaching oligoether appendages to a benzyl substituent on imidazole- or aminopyridine-based active units, presumably because of stabilizing n-cation interactions of the ethereal oxygens with the positively charged aza-heterocycle in the catalytic intermediates, and was substantially higher than that of known benchmark catalysts for a range of substrates. Density functional theory calculations and the study of analogues having a lower potential for such stabilizing interactions support our hypothesis.
DBN hexafluorophosphate salts as convenient sulfonylating and phosphonylating agents
Jones, Caroline S.,Bull, Steven D.,Williams, Jonathan M. J.
, p. 8452 - 8456 (2016/09/28)
Air-stable N-sulfonyl and N-phosphonyl DBN hexafluorophosphate salts have been synthesised under mild conditions as sulfonylating and phosphonylating agents. These salts are highly efficient in the sulfonylation and phosphonylation of a range of N- and O-nucleophiles to generate sulfonamides, sulfonate esters, phosphoramidates and phosphonate esters in good yields.
Organocatalytic phosphorylation of alcohols using pyridine- N -oxide
Murray, James I.,Woscholski, Rudiger,Spivey, Alan C.
supporting information, p. 985 - 990 (2015/04/27)
Phosphorylation of alcohols by phosphoryl chlorides catalysed by pyridine-N-oxide is reported. The utility of this method is demonstrated through phosphorylation of primary, secondary and a tertiary alcohol as well as phenols under mild reaction conditions and with low catalyst loading (5 mol%).
PROCESS FOR PREPARATION OF PHOSPHORIC ESTERS
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Page 7-8, (2010/11/30)
A process for preparing a phosphoric ester, comprising: Step (1) of reacting naphthol with phosphorus oxychloride in a molar ratio of 1:1.3 or more in the presence of a metallic halide and removing unreacted phosphorus oxychloride and Step (2) of reacting the reaction product of Step (1) with phenol in a molar ratio (molar ratio of chlorine contained in the reaction product to phenol) of 1:1-1.5 and removing hydrogen chloride produced as a by-product to thereby obtain a phosphoric ester represented by the general formula (I): wherein n is 1 or 2.
