18872-82-7Relevant academic research and scientific papers
Cobalt-Catalyzed Markovnikov-Selective Radical Hydroacylation of Unactivated Alkenes with Acylphosphonates
Fang, Yewen,He, Jiayan,Li, Chaozhong,Li, Yi,Song, Tao,Zhang, Benxiang
supporting information, p. 4955 - 4961 (2021/05/04)
Acylphosphonates having the 5,5-dimethyl-1,3,2-dioxophosphinanyl skeleton are developed as efficient intermolecular radical acylation reagents, which enable the cobalt-catalyzed Markovnikov hydroacylation of unactivated alkenes at room temperature under mild conditions. The protocol exhibits broad substrate scope and wide functional group compatibility, providing branched ketones in satisfactory yields. A mechanism involving the Co-H mediated hydrogen atom transfer and subsequent trapping of alkyl radicals by acylphosphonates is proposed.
Phosphono-replaced methyl alcohol derivative, and preparation method and application thereof
-
Paragraph 0017, (2017/08/28)
The invention discloses a phosphono-replaced methyl alcohol derivative, and a preparation method and application thereof. The phosphono-replaced methyl alcohol derivative has the advantages that a (hetero) aryl methyl alcohol derivate serves as an initiator, and raw materials are easy to get and have great varieties; products obtained according to the preparation method have various types and wide application ranges, and serve as ligands which coordinate with rhodium to obtain various aldehydes through catalyzed synthesis; the phosphono-replaced (hetero) aryl methyl alcohol can be transformed into phosphonic compounds conveniently; the phosphonic compounds serving as photoinitiators can be widely applied to production of high polymer materials, paint, binders, adhesive tapes and the like. The preparation method has the advantages that reactions are achieved in the air, reaction conditions are mild, yield of target products is high, pollution is small, reaction operations and post-treatment processes are simple, and the preparation method is suitable for industrial production.
Microwave-assisted synthesis of α-hydroxybenzylphosphonates and -benzylphosphine oxides
Keglevich, Gyoergy,Toth, Viola Roza,Drahos, Laszo
experimental part, p. 15 - 17 (2011/10/09)
A series of α-hydroxy-benzylphosphonates and -benzylphosphine oxides was synthesized by the Na2CO3-catalyzed microwave-assisted addition of dialkyl phosphites and dipenylphosphine oxide to P-substituted benzaldehydes. The solventless reaction provided the products in short reaction times and in 71-88% yield.
