188853-28-3Relevant academic research and scientific papers
Use of enzyme penicillin acylase in selective amidation/amide hydrolysis to resolve ethyl 3-amino-4-pentynoate isomers
Topgi, Ravindra S.,Ng, John S.,Landis, Bryan,Wang, Ping,Behling, James R.
, p. 2221 - 2229 (1999)
The β-amino acid, (S)-ethyl-3-amino-4-pentynoate, is a chiral synthon used in the synthesis of xemilofiban hydrochloride, an anti-platelet agent. A biocatalytic approach was developed to resolve (R)- and (S)-enantiomers of ethyl 3-amino-4-pentynoate in en
