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Hydroxytanshinone IIA is a chemical compound derived from the roots of the plant Salvia miltiorrhiza, commonly known as Danshen. It has been traditionally utilized in Chinese herbal medicine for its anti-inflammatory and cardiovascular protective properties. Hydroxytanshinone IIA exhibits potent antioxidant, anti-inflammatory, and antitumor activities, along with protective effects on the cardiovascular system, including reducing blood pressure, inhibiting platelet aggregation, and safeguarding against myocardial ischemia. Furthermore, Hydroxytanshinone IIA has shown promise in the treatment of diabetes, neurodegenerative diseases, and liver fibrosis, making it a versatile and promising compound for various therapeutic applications.

18887-18-8

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18887-18-8 Usage

Uses

Used in Cardiovascular Applications:
Hydroxytanshinone IIA is used as a cardiovascular protective agent for its ability to reduce blood pressure, inhibit platelet aggregation, and protect against myocardial ischemia, thereby contributing to the maintenance of cardiovascular health.
Used in Antioxidant and Anti-inflammatory Applications:
Hydroxytanshinone IIA is used as an antioxidant and anti-inflammatory agent due to its potent activities in neutralizing free radicals and reducing inflammation, which can be beneficial in the treatment of various inflammatory conditions.
Used in Anticancer Applications:
Hydroxytanshinone IIA is used as an anticancer agent for its potential to inhibit tumor growth and progression, making it a candidate for further research and development in oncology.
Used in Diabetes Treatment:
Hydroxytanshinone IIA is used as a therapeutic agent in diabetes treatment, where it may help in managing blood sugar levels and improving overall metabolic health.
Used in Neurodegenerative Disease Treatment:
Hydroxytanshinone IIA is used as a neuroprotective agent in the treatment of neurodegenerative diseases, potentially slowing down disease progression and improving neurological function.
Used in Liver Fibrosis Treatment:
Hydroxytanshinone IIA is used as a therapeutic agent in the treatment of liver fibrosis, where it may help in reducing liver scarring and improving liver function.

Check Digit Verification of cas no

The CAS Registry Mumber 18887-18-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,8,8 and 7 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 18887-18:
(7*1)+(6*8)+(5*8)+(4*8)+(3*7)+(2*1)+(1*8)=158
158 % 10 = 8
So 18887-18-8 is a valid CAS Registry Number.

18887-18-8Upstream product

18887-18-8Relevant academic research and scientific papers

Application of tanshinone II A derivative in drugs

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Paragraph 0048; 0071; 0073, (2016/12/22)

Tanshinone II A compounds are main lipid-soluble components of traditional Chinese medicine salviamiltiorrhiza btmge and have extensive pharmacological activity; the invention belongs to the technical fields of medicinal chemistry and drugs, and in particular, relates to the tanshinone II A derivatives (I), (II), (III) and (IV); the derivatives have good antitumor activity, and can be used for preparation of antitumor drugs.

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