188916-67-8 Usage
Uses
(S)-(3-(3,4-dichlorophenyl)-3-(3-iodopropyl)piperidin-1-yl)(phenyl)methanone can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly for laboratory research and development process and chemical production process.
Check Digit Verification of cas no
The CAS Registry Mumber 188916-67-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,8,9,1 and 6 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 188916-67:
(8*1)+(7*8)+(6*8)+(5*9)+(4*1)+(3*6)+(2*6)+(1*7)=198
198 % 10 = 8
So 188916-67-8 is a valid CAS Registry Number.
188916-67-8Relevant articles and documents
A practical and scalable synthesis of SR 142801, a tachykinin NK3 antagonist
Chen, Huai G.,Chung,Goel,Johnson,Kesten,Knobelsdorf,Lee,Rubin
, p. 555 - 560 (2007/10/03)
A practical and scalable total synthesis of tachykinin NK3 receptor antagonist SR 142801, (R)-N-[1-[3-[1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4 -piperidinyl]-N-methyl acetamide 1 is described. The absolute configuration of the key intermediate 7 was determined by single crystal X-ray crystallography, on the basis of which, the absolute configuration of SR 142801 should be (R)-(+), instead of the recently reported (S)-(+).
