188916-70-3

Basic information

• Product Name: N-methyl-N-(4-phenylpiperidin-4-yl)acetamide hydrochloride
• Synonyms: N-methyl-N-(4-phenylpiperidin-4-yl)acetamide hydrochloride;N-METHYL-N-(4-PHENYLPIPERIDIN-4-YL)ACETAMIDE HCL
• CAS NO: 188916-70-3
• Molecular Formula: C14H21ClN2O
• Molecular Weight: 269
• Mol File: 188916-70-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-methyl-N-(4-phenylpiperidin-4-yl)acetamide hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyl-N-(4-phenylpiperidin-4-yl)acetamide hydrochloride(188916-70-3)
• EPA Substance Registry System: N-methyl-N-(4-phenylpiperidin-4-yl)acetamide hydrochloride(188916-70-3)

Safety Data

• Hazardous Substances Data: 188916-70-3(Hazardous Substances Data)

Upstream product

• 181641-53-2 1-Benzyl-4-(formylamino)-4-phenylpiperidine 
• 172734-03-1 1-Benzyl-4-(methylamino)-4-phenylpiperidine 
• 63843-83-4 1-benzyl-4-hydroxy-4-phenylpiperidine 

Relevant articles and documents

A practical and scalable synthesis of SR 142801, a tachykinin NK3 antagonist

A practical and scalable total synthesis of tachykinin NK3 receptor antagonist SR 142801, (R)-N-[1-[3-[1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4 -piperidinyl]-N-methyl acetamide 1 is described. The absolute configuration of the key intermediate 7 was determined by single crystal X-ray crystallography, on the basis of which, the absolute configuration of SR 142801 should be (R)-(+), instead of the recently reported (S)-(+).