188956-91-4Relevant academic research and scientific papers
Two optimized synthetic pathways toward a chiral precursor of Mivacurium chloride and other skeletal muscle relaxants
Vilhanová, Beáta,Matou?ek, Václav,Václavík, Ji?í,Syslová, Kamila,P?ech, Jan,Pechá?ek, Jan,?ot, Petr,Janu??ák, Jakub,Toman, Jaromír,Zápal, Jakub,Kuzma, Marek,Ka?er, Petr
, p. 50 - 55 (2013)
A chiral precursor of Mivacurium chloride, (R)-5′-methoxylaudanosine, was prepared using two different methods. The chiral resolution of racemic 5′-methoxylaudanosine, typically used in industry, was carried out in parallel with a procedure consisting of
Enantioselective catalytic reduction of dihydroisoquinoline derivatives
Kang, Jahyo,Kim, Jin Bum,Cho, Kwi Hyung,Cho, Byung Tae
, p. 657 - 660 (1997)
Thiazazincolidine complexes, 2, were shown to be excellent catalysts for enantioselective reduction of dihydroisoquinolines 1 with BH3 · THF to the corresponding amines in good ee.
