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188978-02-1

DMP 851 is a P1/P1′ substituted 3-aminoindazole cyclic urea HIV protease inhibitor developed to enhance intracellular antiviral potency by optimizing cell penetration through structural modifications. It exhibits enzyme binding affinity, whole-cell antiviral activity, and pharmacokinetic properties relevant to HIV protease inhibition, positioning it as a potential therapeutic candidate for HIV treatment.

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  • 188978-02-1 Structure

  • Basic information

    1. Product Name: DMP 851
    2. Synonyms: DMP 851
    3. CAS NO:188978-02-1
    4. Molecular Formula: C31H37N5O3
    5. Molecular Weight: 527.65718
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 188978-02-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: DMP 851(CAS DataBase Reference)
    10. NIST Chemistry Reference: DMP 851(188978-02-1)
    11. EPA Substance Registry System: DMP 851(188978-02-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 188978-02-1(Hazardous Substances Data)

188978-02-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 188978-02-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,8,9,7 and 8 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 188978-02:
(8*1)+(7*8)+(6*8)+(5*9)+(4*7)+(3*8)+(2*0)+(1*2)=211
211 % 10 = 1
So 188978-02-1 is a valid CAS Registry Number.

188978-02-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (4R,5S,6S,7R)-1-[(3-amino-1H-indazol-5-yl)methyl]-4,7-dibenzyl-3-butyl-5,6-dihydroxy-1,3-diazepan-2-one

1.2 Other means of identification

Product number -
Other names XQ-443

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:188978-02-1 SDS

188978-02-1Downstream Products

188978-02-1Relevant articles and documents

Synthesis, antiviral activity and pharmacokinetics of P1/P1′ substituted 3-aminoindazole cyclic urea HIV protease inhibitors

Kaltenbach III, Robert F.,Patel, Mona,Waltermire, Robert E.,Harris, Gregory D.,Stone, Benjamin R. P.,Klabe, Ronald M.,Garber, Sena,Bacheler, Lee T.,Cordova, Beverly C.,Logue, Kelly,Wright, Matthew R.,Erickson-Viitanen, Susan,Trainor, George L.

, p. 605 - 608 (2007/10/03)

A series of P1/P1′ substituted cyclic urea analogues were prepared in an attempt to increase the intra-cellular antiviral potency of the nonsymmetrical 3-aminoindazoles DMP 850 and DMP 851. The effect of alkyl substitution of the P1/P1′ residues on cellul

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