188990-59-2Relevant academic research and scientific papers
Stereospecific alkenylation of C-H bonds via reaction with β- heteroatom-functionalized trisubstituted vinyl triflones
Xiang, Jason,Jiang, Wanlong,Gong, Jianchun,Fuchs
, p. 4123 - 4129 (1997)
Aryl and alkyl β-heteroatom-trisubstituted vinyl triflones react with THF and cyclohexane to undergo trifluoromethyl radical-mediated C-H functionalization reactions to afford E and Z β-heteroatom-trisubstituted olefins. Most reactions proceed with both high yield and high stereospecificity (retention of configuration). β-Substituents which have been employed in this study are iodine, bromine, fluorine, benzoate, ethylcarbonate, and phthalimide. β-Substituents bearing powerful electron- releasing groups such as alkoxy or amino render the vinyl triflone unreactive.
