189014-01-5

Basic information

• Product Name: Benzenepropanoic acid, b-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-
• CAS NO: 189014-01-5
• Molecular Formula: C15H21NO4
• Molecular Weight: 279.336
• Mol File: 189014-01-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzenepropanoic acid, b-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, b-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-(189014-01-5)
• EPA Substance Registry System: Benzenepropanoic acid, b-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-(189014-01-5)

Safety Data

• Hazardous Substances Data: 189014-01-5(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 3060-41-1 (±)-3-carboxy-2-phenylpropan-1-aminium chloride 
• 1078-21-3 4-amino-3-phenylbutanoic acid 

Downstream Products

• 189014-03-7 (3-Hydroxycarbamoyl-2-phenyl-propyl)-carbamic acid tert-butyl ester 
• 189014-02-6 4-tert-Butoxycarbonylamino-3-phenyl-butyric acid 2,5-dioxo-pyrrolidin-1-yl ester 

Relevant articles and documents

FUSED [1,2,4]THIADIAZINE DERIVATIVES WHICH ACT AS KAT INHIBITORS OF THE MYST FAMILY

A compound of formula (I): which inhibits the activity of one or more KATs of the MYST family, i.e., TIP60, KAT6B, MOZ, HBO1 and MOF.

HETEROARYL-CARBOXYLIC ACIDS AS HISTONE DEMETHYLASE INHIBITORS

The invention relates to heteroaryl-carboxylic acids as described herein, useful as histone demethylase inhibitors. The invention also relates to pharmaceutical compositions comprising these compounds and to their use in therapy, including e.g., in the treatment of cancer.