189032-31-3Relevant articles and documents
Brewers' yeast-mediated synthesis of (1S,2S)-1-(2-thienyl)-1,2-propanediol and a study on the lipase-catalyzed regioselective introduction of acyl protective group to the diol moiety
Mochizuki, Naoki,Sugai, Takeshi,Ohta, Hiromichi,Yokomatsu, Tsutomu,Shibuya, Shiroshi
, p. 331 - 338 (1997)
Reductive homologation of thiophenecarboxyaldehyde mediated by brewers' yeast and subsequent recrystallization provided (1S,2S)-1-(2-thienyl)-1,2-propanediol in 29% yield. A Pseudomonas lipase-catalyzed acetylation preferentially occurred on the hydroxyl group at C-1 position of the diol.