18904-53-5 Usage
Uses
Used in Research Applications:
Z-VAL-TRP-OH is used as a research tool for studying enzyme kinetics, protein-protein interactions, and peptide-receptor interactions due to its stability and structural properties.
Used in Pharmaceutical Development:
In the pharmaceutical industry, Z-VAL-TRP-OH is used as a building block for the synthesis of larger peptides and proteins, contributing to the development of novel therapeutic agents.
Used in Immunomodulation:
Z-VAL-TRP-OH is used as an immunomodulatory agent for its potential to modulate immune responses, which can be beneficial in treating various immune-related conditions.
Used in Anticancer Applications:
Z-VAL-TRP-OH is investigated as a potential anticancer agent, with its properties being studied for their effects on cancer cell behavior and potential integration into cancer treatment protocols.
Check Digit Verification of cas no
The CAS Registry Mumber 18904-53-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,9,0 and 4 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 18904-53:
(7*1)+(6*8)+(5*9)+(4*0)+(3*4)+(2*5)+(1*3)=125
125 % 10 = 5
So 18904-53-5 is a valid CAS Registry Number.
InChI:InChI=1/C16H22N2O4/c1-11(2)14(15(20)17-12(3)9-19)18-16(21)22-10-13-7-5-4-6-8-13/h4-9,11-12,14H,10H2,1-3H3,(H,17,20)(H,18,21)/t12-,14-/m0/s1
18904-53-5Relevant academic research and scientific papers
Solution-phase synthesis of chiral N-, O-, and S-acyl isopeptides
Liaqat, Sumaira,Panda, Siva S.,Rauf, Abdul,Al-Youbi, Abdulrahman O.,Katritzky, Alan R.
, p. 67 - 72 (2014/01/06)
A convenient synthesis of chiral N-, O-, and S-acyl monoiso- and diisopeptides from di- and tripeptides containing tryptophan, tyrosine, and cysteine units using benzotriazole is reported in solution phase. Georg Thieme Verlag Stuttgart · New York.
Highly diastereoselective peptide chain extensions of unprotected amino acids with N-(Z-α-aminoacyl)benzotriazoles
Katritzky, Alan R.,Suzuki, Kazuyuki,Singh, Sandeep K.
, p. 2645 - 2652 (2007/10/03)
Coupling an unprotected amino acid or dipeptide in partially aqueous solution with a readily available N-(Z-α-amino-acyl)benzotriazole or N-(Z-α-aminopetidoyl)benzotriazole affords N-terminal-protected di-, tri-, and tetrapeptides in yields of 85-98% (average 95% for 2a-i, 93% for 4a-f and 4a′, 86% for 5a-b) with minimal epimerization.
