18905-29-8 Usage
Uses
Used in Pharmaceutical Industry:
Hypoxanthine is used as an antiviral agent for the treatment of viral infections. It inhibits the replication of certain viruses, thereby reducing their ability to infect and damage host cells.
Used in Genetic Disorders Treatment:
Hypoxanthine is used as a treatment for certain genetic disorders, such as Lesch-Nyhan syndrome, a rare X-linked recessive disorder characterized by a deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT). By supplementing hypoxanthine, it can help alleviate some of the symptoms associated with the disorder.
Used in Research and Development:
Hypoxanthine is used as a research tool in the study of purine metabolism, nucleic acid synthesis, and energy transfer processes within cells. It aids in understanding the mechanisms of these biological processes and can contribute to the development of new therapeutic strategies and interventions.
Check Digit Verification of cas no
The CAS Registry Mumber 18905-29-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,9,0 and 5 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 18905-29:
(7*1)+(6*8)+(5*9)+(4*0)+(3*5)+(2*2)+(1*9)=128
128 % 10 = 8
So 18905-29-8 is a valid CAS Registry Number.
InChI:InChI=1/C5H3N5O2/c6-5-9-4(11)2-3(10(5)12)8-1-7-2/h1H,(H2,6,9,11)
18905-29-8Relevant academic research and scientific papers
Schmidt, Andreas,Kobakhidze, Nikoloz
, p. 222 - 223 (2002)
Substitution of 8-H of guanine-N-oxide was accomplished by pyridine, 4-dimethylaminopyridine and acetyl chloride, respectively, to give a cationic purine base after hydrolysis. Deprotonation formed mesomeric betaines of guanine. ESI mass spectrometry and