18908-55-9 Usage
Description
3-[cyano(phenyl)methyl]benzoic acid is a chemical compound characterized by its molecular formula C15H11NO2. It is a white to light yellow crystalline powder with slight solubility in water. As a derivative of benzoic acid, it features a cyano group attached to the benzene ring, which, along with the phenylmethyl group, endows it with unique chemical properties. 3-[cyano(phenyl)methyl]benzoic acid is recognized for its role as an intermediate in the synthesis of various organic compounds, particularly in the pharmaceutical and agrochemical industries, due to its ability to participate in a wide range of chemical reactions, making it a versatile building block for more complex molecules.
Uses
Used in Pharmaceutical Industry:
3-[cyano(phenyl)methyl]benzoic acid is used as a key intermediate in the synthesis of pharmaceuticals for its capacity to form complex molecular structures. The presence of the cyano and phenylmethyl groups allows for the creation of new drugs with specific therapeutic properties, contributing to the development of novel treatments for various medical conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 3-[cyano(phenyl)methyl]benzoic acid serves as an essential intermediate in the production of pesticides. Its chemical versatility facilitates the design of effective compounds targeting pests and diseases, thereby enhancing crop protection and contributing to increased agricultural productivity.
Used in Research and Development:
3-[cyano(phenyl)methyl]benzoic acid is utilized in research and development as a versatile compound for exploring new chemical reactions and syntheses. Its potential to undergo various transformations makes it a valuable tool for scientists working on innovative organic chemistry and the discovery of new chemical entities with potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 18908-55-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,9,0 and 8 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 18908-55:
(7*1)+(6*8)+(5*9)+(4*0)+(3*8)+(2*5)+(1*5)=139
139 % 10 = 9
So 18908-55-9 is a valid CAS Registry Number.
18908-55-9Relevant articles and documents
Preparation of 2-Cyanobenzoic Acids from the Reaction of Bromobenzoic Acids with Arylacetonitriles and LDA
Wang, Anlai,Maguire, John A.,Biehl, Ed
, p. 2451 - 2455 (2007/10/03)
The reaction of various bromobenzoic acids 1 with arylacetonitriles 3 in the presence of LDA at -70°C gave predominantly 2-cyanobenzoic acids 4 plus minor amounts of 3-(arylcyanomethyl)-benzoic acids 5 and debrominated benzoic acids 6. The reaction is thought to proceed through a benzyne-3-carboxylate intermediate 2, which is formed at -70°C upon the addition of the arylacetonitrile 3 to a solution of the appropriate lithium halobenzoate and excess LDA. The base-initiated generation of an aryne intermediate from a haloarene at such low temperatures is unprecedented. To confirm the orientation of the cyano and carboxylic acid groups, 4-methoxy-2-cyanobenzoic acid (4f) was converted to the corresponding anhydride (8) via phthalic acid (7) and to 3,3-dimethyl- and 3,3-di-n-butyl-2,3-dihydro-5-methoxy-4-(4-methoxyphenyl)-methyl-1H-isoindol-1- ones (9).
