1891-14-1

Usage

Uses

Used in Analytical Chemistry:
4-Chloro-1,10-phenanthroline is used as a chelating agent for the detection and analysis of metal ions. Its complexes with transition metal ions are often used in spectrophotometric methods to determine the concentration of these metals in various samples.
Used in Biochemistry:
In biochemistry, 4-Chloro-1,10-phenanthroline is used as a reagent to study the interactions between metal ions and biomolecules. Its complexes with metal ions can help in understanding the role of these ions in biological processes and their potential involvement in diseases.
Used in Environmental Science:
4-Chloro-1,10-phenanthroline is employed in environmental science for the detection and analysis of metal ions in water, soil, and air samples. Its complexes with metal ions can be used to monitor the presence of heavy metals and assess the environmental impact of metal pollution.
Used in Medicinal Chemistry and Pharmacology Research:
4-Chloro-1,10-phenanthroline has been found to exhibit potential biological activities, making it a subject of interest in medicinal chemistry and pharmacology research. Its complexes with metal ions may have therapeutic applications, and further studies are being conducted to explore their potential as drug candidates.

Upstream product

• 93533-15-4 1H-1,10-phenanthrolin-4-one 
• 25063-76-7 2,2-Dimethyl-5-(quinolin-8-ylaminomethylene)-[1,3]dioxane-4,6-dione 
• 86443-19-8 ethyl 4-oxo-1,4-dihydro-1,10-phenanthroline-3-carboxylate 
• 53946-49-9 4-oxo-1,4-dihydro-[1,10]phenanthroline-3-carboxylic acid 
• 578-66-5 8-amino quinoline 
• 23443-31-4 4-hydroxy-1,10-phenanthroline 
• 130728-49-3 diethyl [(quinolin-8-ylamino)methylene]malonate 

Relevant academic research and scientific papers

New nonsymmetric phenanthrolines as very effective ligands in the palladium-catalyzed carbonylation of nitrobenzene

Inspired by the results of a previous mechanistic study, a series of mostly new nonsymmetric phenanthrolines were synthesized and tested as ligands in the palladium-catalyzed reductive carbonylation reaction of nitrobenzene to methyl phenylcarbamate. Very good results were obtained when the asymmetry was of an electronic nature (a donating substituent in the para position of one of the two pyridinic rings and an electron-withdrawing or no substituent on the para position of the other pyridinic ring), but steric hindrance in the ortho or meta position retarded the reaction. The TOF for the modified system is the highest ever reported for any carbonylation reaction of nitroarenes.

Palladium-Catalyzed Intramolecular Cyclization of Nitroalkenes: Synthesis of Thienopyrroles

In the presence of carbon monoxide, the palladium/phenanthroline system catalyzes the intramolecular amination of thiophene rings following the reduction of a nitroalkene moiety directly attached to the S-heterocyclic ring. Optimization of the ligand and reaction conditions allowed the synthesis of a series of thienopyrroles aryl/alkyl-substituted at either the 2- or 3-position of the pyrrole ring. By using low pressures of carbon monoxide (5 bars), high yields of fused bicyclic compounds have been obtained (up to 98 % yield).

Luminescent Metal Complexes. Part 5. Luminescence Properties of Ring-substituted 1,10-Phenanthroline Tris-complexes of Ruthenium(II)

The absorption characteristics, emission spectra, luminescent quantum yields, and lifetimes are reported for 24 ruthenium(II) tris-1,10-phenanthroline complexes in EtOH-MeOH solution.Quantum yields fall between 0.019 and 0.403, the highest values being re