23443-31-4

Basic information

• Product Name: 1,10-Phenanthrolin-4-ol
• Synonyms: 1,10-Phenanthrolin-4-ol;4-Hydroxy-1,10-phenanthroline
• CAS NO: 23443-31-4
• Molecular Formula: C12H8N2O
• Molecular Weight: 196.20472
• Mol File: 23443-31-4.mol

Chemical Properties

• Melting Point: 214-215℃
• Boiling Point: 389 °C at 760 mmHg
• Flash Point: 189.1 °C
• Appearance: /
• Density: 1.313 g/cm³
• PKA: 8.61±0.10(Predicted)
• CAS DataBase Reference: 1,10-Phenanthrolin-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,10-Phenanthrolin-4-ol(23443-31-4)
• EPA Substance Registry System: 1,10-Phenanthrolin-4-ol(23443-31-4)

Safety Data

• Hazardous Substances Data: 23443-31-4(Hazardous Substances Data)

Usage

Uses

Used in Biochemical Research:
1,10-Phenanthrolin-4-ol is used as a chelating agent for [forming complexes with metal ions] in biochemical research. Its ability to bind with metal ions makes it a valuable tool in studying metal ion interactions and their roles in biological systems.
Used in Chemical Reactions:
1,10-Phenanthrolin-4-ol is used as a reducing agent for [facilitating certain chemical reactions] in the field of chemistry. Its reducing properties allow it to participate in various chemical processes, contributing to the synthesis of different compounds.
Used in Analytical Chemistry:
1,10-Phenanthrolin-4-ol is used as an analytical reagent for [determining the presence and concentration of metal ions] in analytical chemistry. Its complex-forming ability with metal ions enables accurate detection and quantification of these ions in various samples.
Used in Environmental Science:
1,10-Phenanthrolin-4-ol is used as an environmental tracer for [tracking the movement and distribution of metal ions in the environment]. This application aids in understanding the behavior of metal ions in ecosystems and their potential impact on the environment.

Upstream product

• 25063-76-7 2,2-Dimethyl-5-(quinolin-8-ylaminomethylene)-[1,3]dioxane-4,6-dione 

Downstream Products

• 7089-67-0 4-bromo-1,10-phenanthroline 
• 1891-14-1 4-chloro-1,10-phenanthroline 

Relevant articles and documents

Palladium-Catalyzed Intramolecular Cyclization of Nitroalkenes: Synthesis of Thienopyrroles

In the presence of carbon monoxide, the palladium/phenanthroline system catalyzes the intramolecular amination of thiophene rings following the reduction of a nitroalkene moiety directly attached to the S-heterocyclic ring. Optimization of the ligand and reaction conditions allowed the synthesis of a series of thienopyrroles aryl/alkyl-substituted at either the 2- or 3-position of the pyrrole ring. By using low pressures of carbon monoxide (5 bars), high yields of fused bicyclic compounds have been obtained (up to 98 % yield).

New nonsymmetric phenanthrolines as very effective ligands in the palladium-catalyzed carbonylation of nitrobenzene

Inspired by the results of a previous mechanistic study, a series of mostly new nonsymmetric phenanthrolines were synthesized and tested as ligands in the palladium-catalyzed reductive carbonylation reaction of nitrobenzene to methyl phenylcarbamate. Very good results were obtained when the asymmetry was of an electronic nature (a donating substituent in the para position of one of the two pyridinic rings and an electron-withdrawing or no substituent on the para position of the other pyridinic ring), but steric hindrance in the ortho or meta position retarded the reaction. The TOF for the modified system is the highest ever reported for any carbonylation reaction of nitroarenes.